SCHEMBL16781065

SCHEMBL16781065

NC(=O)Sc1c[nH]c2ccccc12

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ IDO1 P14902 1/20 0.70
▸ STAT3 P40763 2/20 0.64
▸ ALDH1A1 P00352 1/20 0.56
▸ ATM Q13315 1/20 0.56
▸ GFER P55789 3/20 0.51
▸ TUBB4A P04350 1/20 0.51
▸ TUBB P07437 1/20 0.51
▸ TUBA3C P0DPH7 1/20 0.51
▸ TUBA1B P68363 1/20 0.51
▸ TUBA4A P68366 1/20 0.51
▸ TUBB4B P68371 1/20 0.51
▸ TUBB3 Q13509 1/20 0.51
▸ TUBB2A Q13885 1/20 0.51
▸ TUBB8 Q3ZCM7 1/20 0.51
▸ TUBA3E Q6PEY2 1/20 0.51
▸ TUBA1A Q71U36 1/20 0.51
▸ TUBA1C Q9BQE3 1/20 0.51
▸ TUBB6 Q9BUF5 1/20 0.51
▸ TUBB2B Q9BVA1 1/20 0.51
▸ TUBB1 Q9H4B7 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28274750 0.82 IDO1 (0.70) IDO1STAT3ALDH1A1ATMGFER
SCHEMBL29459637 0.82 IDO1 (1.00) IDO1STAT3ALDH1A1ATMGFER
SCHEMBL6082138 0.82 IDO1 (1.00) IDO1STAT3ALDH1A1ATMGFER
SCHEMBL9161820 0.82 IDO1 (0.60) IDO1STAT3ALDH1A1ATMGFER
SCHEMBL29009232 0.81 IDO1 (0.68) IDO1STAT3ALDH1A1ATMGFER
Iodide SCHEMBL6082236 0.81 IDO1 (0.97) IDO1STAT3ALDH1A1ATMGFER
SCHEMBL11612865 0.74 IDO1 (0.51) IDO1STAT3ALDH1A1GFERTUBB4A
SCHEMBL17758429 0.74 IDO1 (0.51) IDO1STAT3GFERTUBB4ATUBB
SCHEMBL11614606 0.74 IDO1 (0.51) IDO1STAT3ALDH1A1GFERTUBB4A
SCHEMBL9328490 0.74 TUBB4A (0.64) IDO1STAT3ATMGFERTUBB4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250092487-A1 METHODS FOR LIBERATING PRECIOUS METALS USING A REAGENT HAVING A THIOCARBONYL FUNCTIONAL GROUP JETTI RESOURCES, LLC (US) 2025-03-20 — — US claimed
EP-3283661-B1 PROCESS FOR LEACHING METAL SULFIDES WITH REAGENTS HAVING THIOCARBONYL FUNCTIONAL GROUPS JETTI RESOURCES LLC (US) 2024-06-05 — — EP claimed
WO-2022245731-A1 METHODS FOR LIBERATING PRECIOUS METALS USING A REAGENT HAVING A THIOCARBONYL FUNCTIONAL GROUP JETTI RESOURCES, LLC (US) 2022-11-24 — — WO claimed
CN-107532229-B Process for leaching metal sulphides with an agent having a thiocarbonyl function 不列颠哥伦比亚大学 2021-10-08 — — CN claimed
US-20150164860-A1 ANTICANCER TREATMENT METHODS INVOLVING ANALOGS AND DERIVATIVES OF 3-(2-SUBSTITUTED-ETHYL) INDOLE COMPOUNDS TUSKEGEE UNIVERSITY (US) 2015-06-18 — — US claimed
EP-4214343-B1 EXTRACTING BASE METALS USING A WETTING AGENT AND A THIOCARBONYL FUNCTIONAL GROUP REAGENT JETTI RESOURCES LLC (US) 2026-05-06 — — EP disclosed
US-20250179610-A1 EXTRACTION OF BASE METALS USING CARBONACEOUS MATTER AND A THIOCARBONYL FUNCTIONAL GROUP REAGENT JETTI RESOURCES, LLC (US) 2025-06-05 — — US disclosed
US-20250179607-A1 EXTRACTING BASE METALS USING A WETTING AGENT AND A THIOCARBONYL FUNCTIONAL GROUP REAGENT JETTI RESOURCES, LLC (US) 2025-06-05 — — US disclosed
US-20250115595-A1 INHIBITORS OF HYPOXIA-INDUCIBLE FACTORS THE JOHNS HOPKINS UNIVERSITY 2025-04-10 — — US disclosed
US-12264381-B2 Extracting base metals using a wetting agent and a thiocarbonyl functional group reagent JETTI RESOURCES, LLC (US) 2025-04-01 — — US disclosed
US-20250092487-A1 METHODS FOR LIBERATING PRECIOUS METALS USING A REAGENT HAVING A THIOCARBONYL FUNCTIONAL GROUP JETTI RESOURCES, LLC (US) 2025-03-20 — — US disclosed
US-12247266-B2 Extraction of base metals using carbonaceous matter and a thiocarbonyl functional group reagent JETTI RESOURCES, LLC (US) 2025-03-11 — — US disclosed
WO-2023018747-A1 INHIBITORS OF HYPOXIA-INDUCIBLE FACTORS THE JOHNS HOPKINS UNIVERSITY (US) 2023-02-16 — — WO disclosed
CN-110352256-B Process for leaching metal sulphides with an agent having a thiocarbonyl function 捷迪资源有限责任公司 2023-01-10 — — CN disclosed
WO-2022056622-A1 EXTRACTING BASE METALS USING A WETTING AGENT AND A THIOCARBONYL FUNCTIONAL GROUP REAGENT THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2022-03-24 — — WO disclosed
CN-107532229-B Process for leaching metal sulphides with an agent having a thiocarbonyl function 不列颠哥伦比亚大学 2021-10-08 — — CN disclosed
CN-111850294-A Process for leaching metal sulphides with an agent having a thiocarbonyl function 不列颠哥伦比亚大学 2020-10-30 — — CN disclosed
US-9877949-B2 Anticancer treatment methods involving analogs and derivatives of 3-(2-substituted-ethyl) indole compounds TUSKEGEE UNIVERSITY (US) 2018-01-30 — — US disclosed
WO-2017027739-A1 COPOLYMERIZATION OF ELEMENTAL SULFUR AND THIOCARBONYL-CONTAINING COMPOUNDS THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2017-02-16 — — WO disclosed
US-20150164860-A1 ANTICANCER TREATMENT METHODS INVOLVING ANALOGS AND DERIVATIVES OF 3-(2-SUBSTITUTED-ETHYL) INDOLE COMPOUNDS TUSKEGEE UNIVERSITY (US) 2015-06-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150164860-A1 ANTICANCER TREATMENT METHODS INVOLVING ANALOGS AND DERIVATIVES OF 3-(2-SUBSTITUTED-ETHYL) INDOLE COMPOUNDS MCL1, BAD, API5 IDO1 17/4885STAT3 785/4885ALDH1A1 724/4885
US-20250115595-A1 INHIBITORS OF HYPOXIA-INDUCIBLE FACTORS HIF1AN, HIF1A, EGLN2 IDO1 1815/4885STAT3 20/4885ALDH1A1 571/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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