Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.70 |
| ▸ | STAT3 | P40763 | 2/20 | 0.55 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.51 |
| ▸ | TUBB | P07437 | 1/20 | 0.51 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.51 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.51 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.51 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.51 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.51 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.51 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.51 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.51 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.51 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.51 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.51 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.51 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29009232 | 0.98 | IDO1 (0.68) | IDO1STAT3TUBB4ATUBBTUBA3C | |
| SCHEMBL16781065 | 0.82 | IDO1 (0.70) | IDO1STAT3TUBB4ATUBBTUBA3C | |
| SCHEMBL29459637 | 0.82 | IDO1 (1.00) | IDO1STAT3TUBB4ATUBBTUBA3C | |
| SCHEMBL6082138 | 0.82 | IDO1 (1.00) | IDO1STAT3TUBB4ATUBBTUBA3C | |
| Iodide SCHEMBL6082236 | 0.81 | IDO1 (0.97) | IDO1STAT3TUBB4ATUBBTUBA3C | |
| SCHEMBL9161820 | 0.75 | IDO1 (0.60) | IDO1STAT3TUBB4ATUBBTUBA3C | |
| SCHEMBL5307941 | 0.74 | TUBB4A (0.77) | IDO1STAT3TUBB4ATUBBTUBA3C | |
| SCHEMBL9328490 | 0.74 | TUBB4A (0.64) | IDO1STAT3TUBB4ATUBBTUBA3C | |
| SCHEMBL16781064 | 0.72 | ALDH1A1 (0.67) | IDO1ATMALDH1A1ASH1LMAPT | |
| SCHEMBL29484326 | 0.72 | ALDH1A1 (0.67) | IDO1ATMALDH1A1ASH1LMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109384702-A | A kind of preparation method of N- dithiocarbamate Benzazole compounds | 温州医科大学 | 2019-02-26 | — | — | CN | claimed |
| CN-117210831-A | Preparation method of imidazopyridine-3-dimethylamino disulfate compound | 上海陶术生物科技有限公司 | 2023-12-12 | — | — | CN | disclosed |
| CN-113880806-B | 2-amino-4-oxo-quinazoline dithiocarbamate derivative, and pharmaceutical composition and application thereof | 深圳大学 | 2022-09-13 | — | — | CN | disclosed |
| CN-113880806-A | 2-amino-4-oxo-quinazoline dithio formate derivative, and pharmaceutical composition and application thereof | 深圳大学 | 2022-01-04 | — | — | CN | disclosed |
| CN-109384702-B | Preparation method of N-dithiocarbamate indole compound | 温州医科大学 | 2020-08-25 | — | — | CN | disclosed |
| CN-109384702-A | A kind of preparation method of N- dithiocarbamate Benzazole compounds | 温州医科大学 | 2019-02-26 | — | — | CN | disclosed |