SCHEMBL1678255

SCHEMBL1678255

CCNC(CC)(CC)CC

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 1/20 0.32
TSHR P16473 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7197318 0.81
SCHEMBL11079221 0.81
SCHEMBL27292738 0.81
SCHEMBL9645109 0.78 TP53 (0.37) TP53
SCHEMBL2349676 0.72 ALDH1A1 (0.31) TSHR
SCHEMBL13946835 0.72 CYP2C19 (0.33)
SCHEMBL19546011 0.72 ADH1B (0.30)
SCHEMBL11426693 0.72
SCHEMBL16229092 0.69 TSHR (0.41) TSHRTDP1
Hydrochloric Acid SCHEMBL11429411 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101443330-A Heterocyclic non-nucleoside compound, preparation method thereof, pharmaceutical composition and application thereof as antiviral inhibitor SHANGHAI INST MATERIA MEDICA (CN) 2009-05-27 CN claimed
EP-2030974-A1 HETEROCYCLIC NON-NUCLEOSIDE COMPOUNDS, THEIR PEPARATION, PHARMACEUTICAL COMPOSITION AND THEIR USE AS ANTIVIRAL AGENTS Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) 2009-03-04 EP claimed
US-20260015341-A1 PI3K INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF HINOVA PHARMACEUTICALS INC (CN) 2026-01-15 US disclosed
EP-4553075-A1 PI3K INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF Hinova Pharmaceuticals Inc. (CN) 2025-05-14 EP disclosed
US-20240368203-A1 DEGRADATION OF (EGFR) BY CONJUGATION OF EGFR INHIBITORS WITH E3 LIGASE LIGAND AND METHODS OF USE BEIGENE, LTD. (KY) 2024-11-07 US disclosed
WO-2024008122-A1 PI3K INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF 海创药业股份有限公司 2024-01-11 WO disclosed
CN-117362576-A Aqueous polyurethane urea dispersions 科思创知识产权两合公司 2024-01-09 CN disclosed
CN-117362281-A PI3K inhibitor and preparation method and application thereof 海创药业股份有限公司 2024-01-09 CN disclosed
CN-113677727-B Aqueous polyurethane urea dispersions 科思创知识产权两合公司 2023-10-31 CN disclosed
WO-2022257960-A1 BICYCLIC COMPOUND FOR THE TREATMENT OF EP2 AND EP4 RECEPTOR-MEDIATED DISEASES 武汉人福创新药物研发中心有限公司 2022-12-15 WO disclosed
CN-115368568-A Perfluorinated ion exchange resin, preparation method thereof and ion exchange membrane 国家电投集团氢能科技发展有限公司 2022-11-22 CN disclosed
EP-1667647-A2 MONOCYCLIC AND BICYCLIC LACTAMS AS FACTOR XA INHIBITORS Bristol-Myers Squibb Company (US) 2006-06-14 EP disclosed
WO-2005061481-A1 NOVEL MA CROCYCLES AND USES THEREOF SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 2005-07-07 WO disclosed
US-20050107361-A1 Monocyclic and bicyclic lactams as factor Xa inhibitors BRISTOL-MYERS SQUIBB COMANY 2005-05-19 US disclosed
WO-2005032468-A2 MONOCYCLIC AND BICYCLIC LACTAMS AS FACTOR XA INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2005-04-14 WO disclosed
WO-2004058713-A1 DIFFERENTIAL TUMOR CYTOTOXOCITY COMPOUNDS AND COMPOSITIONS IRM LLC (BM) 2004-07-15 WO disclosed
US-20040132786-A1 Differential tumor cytotoxicity compounds and compositions IRM LLC, A DELAWARE LIMITED LIABILITY COMPANY (BM) 2004-07-08 US disclosed
US-6069128-A LOW MOLECULAR WEIGHT PEPTIDE CORRESPONDING TO TRANSMEMBRANE REGION OF INTERLEUKIN-8 PROTEIN, TRANSFORMED INTO ITS ACETOXYMETHYL ESTER COUNTERPART AND CONVERTED BACK TO ORGINAL FORM VIA INTRACELLULAR ESTERASE; TREATING INFLAMMATION UNIVERSITE LAVAL (CA) 2000-05-30 US disclosed
EP-0177933-B1 INTERMEDIATES FOR MAKING 16-PHENOXY AND 16-SUBSTITUTED PHENOXY-PROSTATRIENOIC ACID DERIVATIVES SYNTEX (U.S.A.) INC. (US) 1989-05-10 EP disclosed
EP-0177933-A2 Intermediates for making 16-phenoxy and 16-substituted phenoxy-prostatrienoic acid derivatives SYNTEX (U.S.A.) INC. (US) 1986-04-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040132786-A1 Differential tumor cytotoxicity compounds and compositions MIF, FOXM1, MYADM KCNN4 4833/4885TSHR 4210/4885TDP1 731/4885
US-20260015341-A1 PI3K INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF PIK3CA, PIK3R4, PIK3R1 KCNN4 4349/4885TSHR 1648/4885TDP1 3052/4885
US-20240368203-A1 DEGRADATION OF (EGFR) BY CONJUGATION OF EGFR INHIBITORS WITH E3 LIGASE LIGAND AND METHODS OF USE EGFR, CBL, ERBB2 KCNN4 4880/4885TSHR 2105/4885TDP1 3598/4885
US-20050107361-A1 Monocyclic and bicyclic lactams as factor Xa inhibitors F2, F12, SPINT2 KCNN4 1819/4885TSHR 1828/4885TDP1 3738/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.