Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TOP2A | P11388 | 1/20 | 0.33 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20201810 | 0.76 | CRBN (0.41) | CRBNALDH1A1MAPTPOLBTOP2A | |
| SCHEMBL7132617 | 0.76 | CRBN (0.46) | CRBNALDH1A1MAPTPOLBTOP2A | |
| Acetic Acid SCHEMBL6932192 | 0.73 | CRBN (0.39) | CRBNALDH1A1MAPTPOLBTOP2A | |
| Sulfuric Acid SCHEMBL11153071 | 0.71 | CRBN (0.41) | CRBNALDH1A1MAPTTOP2ATOP2B | |
| SCHEMBL8789386 | 0.69 | CRBN (0.34) | CRBNALDH1A1MAPTPOLB | |
| SCHEMBL31058804 | 0.64 | — | — | |
| SCHEMBL30461817 | 0.64 | — | — | |
| Hydrochloric Acid SCHEMBL1126384 | 0.62 | — | — | |
| Creatinine SCHEMBL123387 | 0.61 | CRBN (0.50) | CRBNALDH1A1MAPTTOP2ATOP2B | |
| SCHEMBL2430686 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 255 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104478780-A | Acylpyrrole small-molecular organic compound, derivatives of organic compound as well as application and preparation method of acylpyrrole small-molecular organic compound and derivatives of organic compound | UNIV EAST CHINA NORMAL | 2015-04-01 | — | — | CN | claimed |
| CN-104230834-A | Novel antitumor compounds capable of stabilizing RNA G-quadruplet based on aromatic five-membered ring molecular skeleton | UNIV GUANGDONG TECHNOLOGY | 2014-12-24 | — | — | CN | claimed |
| CN-103923085-A | Pyridine heterocyclic compounds having Hedgehog pathway antagonist activity, and use thereof | SUZHOU YUNXUAN PHARMACEUTICAL CO LTD | 2014-07-16 | — | — | CN | claimed |
| CN-103922981-A | Compound and application thereof | UNIV SOOCHOW | 2014-07-16 | — | — | CN | claimed |
| CN-103842463-A | Heat-ray-shielding adhesive composition and heat-ray-shielding adhesive sheet | NIPPON KAYAKU KK | 2014-06-04 | — | — | CN | claimed |
| CN-103694236-A | Novel antineoplastic compound containing pyrimidine skeleton and hedgehog pathway antagonist activity | SUZHOU YUNXUAN MEDICINE SCIENCE & TECHNOLOGY CO LTD | 2014-04-02 | — | — | CN | claimed |
| CN-103588771-A | Pyrimidine antitumor compound with Hedgehog antagonist activity | SUZHOU YUNXUAN PHARMACEUTICAL CO LTD | 2014-02-19 | — | — | CN | claimed |
| CN-103524535-A | Amido thiazole-pyridine heterocycle compound with activity of hedgehog path antagonist | SUZHOU YUNXUAN PHARMACEUTICAL CO LTD | 2014-01-22 | — | — | CN | claimed |
| CN-103339124-A | Method for producing di(arylamino)aryl compound, and synthetic intermediate therefor | ASTELLAS PHARMA INC | 2013-10-02 | — | — | CN | claimed |
| CN-103275041-A | Five-membered heterocyclic dicarbonyl derivative and applications thereof for resisting multidrug-resistant bacteria | UNIV CHINA PHARMA | 2013-09-04 | — | — | CN | claimed |
| CN-101058561-A | Diphenylurea derivative for inhibiting protein kinase, and composition and use thereof | SUZHOU ASCEPION PHARMACEUTICAL (CN) | 2007-10-24 | — | — | CN | claimed |
| CN-1823057-A | Biaryl piperazinyl-pyridine analogues | NEUROGEN CORP (US) | 2006-08-23 | — | — | CN | claimed |
| CN-1817860-A | Asymmetric bisindole styrene salt compound and high-density recording medium containing the same | IND TECHNOLOGY INST (CN) | 2006-08-16 | — | — | CN | claimed |
| CN-1630709-A | Human glucagon-like-peptide-1 mimics and their use in the treatment of diabetes and related conditions | BRISTOL MYERS SQUIBB CO (US) | 2005-06-22 | — | — | CN | claimed |
| CN-1616426-A | Indole styrene salt compound, high-density recording medium containing the same and process for producing the same | IND TECHNOLOGY INST (CN) | 2005-05-18 | — | — | CN | claimed |
| CN-1552768-A | Optical recording medium dye | 铼德科技股份有限公司 | 2004-12-08 | — | — | CN | claimed |
| CN-1535204-A | Polymeric membranes functionalized with EGTA ligands | IBC | 2004-10-06 | — | — | CN | claimed |
| CN-1302287-A | Bioreductive cytotoxic agents | SHIONOGI BIORES CORP (US) | 2001-07-04 | — | — | CN | claimed |
| CN-1031378-A | Antimicrobial compounds | ICI PLC (GB) | 1989-03-01 | — | — | CN | claimed |
| CN-87103552-A | Adopt malonate derivative to improve crop yield | — | 1988-07-06 | — | — | CN | claimed |