SCHEMBL20201810

SCHEMBL20201810

NS(=O)(=O)N1CC(=O)NC1=O

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 1/20 0.41
ALDH1A1 P00352 3/20 0.36
MAPT P10636 2/20 0.36
POLB P06746 1/20 0.36
TOP2A P11388 1/20 0.33
TOP2B Q02880 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7132617 0.76 CRBN (0.46) CRBNALDH1A1MAPTPOLBTOP2A
SCHEMBL1678327 0.76 CRBN (0.41) CRBNALDH1A1MAPTPOLBTOP2A
SCHEMBL31058804 0.69
SCHEMBL8788699 0.69 CRBN (0.34) CRBNALDH1A1MAPTPOLB
SCHEMBL8789094 0.69 CRBN (0.34) CRBNALDH1A1MAPTPOLB
SCHEMBL8789386 0.69 CRBN (0.34) CRBNALDH1A1MAPTPOLB
Acetic Acid SCHEMBL6932192 0.69 CRBN (0.39) CRBNALDH1A1MAPTPOLBTOP2A
SCHEMBL8972689 0.67 ALDH1A1 (0.69) ALDH1A1MAPTPOLBMEN1KMT2A
Hydrochloric Acid SCHEMBL1126384 0.67
Sulfuric Acid SCHEMBL11153071 0.67 CRBN (0.41) CRBNALDH1A1MAPTTOP2ATOP2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018098206-A1 HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS CV6 THERAPEUTICS (NI) LIMITED (GB) 2018-05-31 WO disclosed