Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | CTSG | P08311 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | CTRC | Q99895 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10169092 | 0.82 | MAPT (0.38) | MAPTTDP1LMNANPSR1L3MBTL1 | |
| SCHEMBL29331244 | 0.81 | MAPT (0.47) | MAPTTDP1LMNANPSR1L3MBTL1 | |
| SCHEMBL22542012 | 0.80 | PIM1 (0.39) | MAPTTDP1LMNANPSR1L3MBTL1 | |
| SCHEMBL12916351 | 0.80 | PIM1 (0.39) | MAPTTDP1LMNANPSR1L3MBTL1 | |
| SCHEMBL13808671 | 0.80 | PIM1 (0.39) | MAPTTDP1LMNANPSR1L3MBTL1 | |
| SCHEMBL21204343 | 0.79 | MAPT (0.36) | MAPTTDP1LMNANPSR1L3MBTL1 | |
| SCHEMBL17642721 | 0.79 | MAPT (0.36) | MAPTTDP1LMNANPSR1L3MBTL1 | |
| SCHEMBL2610122 | 0.78 | SMN1; SMN2 (0.47) | MAPTTDP1LMNANPSR1L3MBTL1 | |
| SCHEMBL19003699 | 0.78 | SMN1; SMN2 (0.47) | MAPTTDP1LMNANPSR1L3MBTL1 | |
| SCHEMBL1071244 | 0.77 | MAPK1 (0.50) | MAPTNPSR1L3MBTL1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9050589-B2 | Alkene aziridination | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2015-06-09 | — | — | US | disclosed |