Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 2/20 | 0.47 |
| ▸ | PRCP | P42785 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15272185 | 0.81 | JAK2 (0.48) | PNMTPRCPCD274HTR6 | |
| SCHEMBL5086121 | 0.81 | PNMT (0.61) | PNMTPRCPCD274 | |
| SCHEMBL16518770 | 0.80 | PNMT (0.48) | PNMTPRCPCD274 | |
| Hydrochloric Acid SCHEMBL11487923 | 0.79 | PNMT (0.59) | PNMTPRCPCD274 | |
| SCHEMBL16784767 | 0.74 | HTR2C (0.35) | CD274 | |
| SCHEMBL915092 | 0.73 | PNMT (0.69) | PNMTPRCPCD274HRH3 | |
| SCHEMBL16518783 | 0.73 | PNMT (0.54) | PNMTPRCPCD274HRH3 | |
| Hydrochloric Acid SCHEMBL1124672 | 0.72 | PNMT (0.68) | PNMTPRCPCD274HRH3 | |
| SCHEMBL11486132 | 0.69 | CD274 (0.65) | PNMTPRCPCD274 | |
| SCHEMBL16518127 | 0.69 | PRCP (0.55) | PNMTPRCPHDAC1HDAC6HDAC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9051311-B2 | Sulfamide sodium channel inhibitors | AMGEN INC. (US) | 2015-06-09 | — | — | US | disclosed |