Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16785677 | 0.90 | ACHE (0.48) | ACHEKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL16785680 | 0.87 | ELANE (0.39) | ACHEKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL16785682 | 0.83 | CYP3A4 (0.38) | ACHEKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL16785667 | 0.81 | ACHE (0.53) | ACHEMAPTALDH1A1HTTLMNA | |
| SCHEMBL16785665 | 0.81 | ACHE (0.53) | ACHEKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL16785678 | 0.79 | ELANE (0.38) | ACHEKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL16785679 | 0.79 | CYP3A4 (0.38) | ACHEKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL16785681 | 0.79 | ELANE (0.38) | ACHEKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL16785670 | 0.78 | ELANE (0.41) | KMT2AMEN1CYP3A4ELANEHPGD | |
| SCHEMBL16785671 | 0.77 | ELANE (0.42) | MAPTALDH1A1HTTLMNAELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9365513-B2 | Fullerene derivative, and method of preparing the same | RICOH COMPANY, LTD. (JP) | 2016-06-14 | — | — | US | disclosed |
| US-9365513-B2 | Fullerene derivative, and method of preparing the same | RICOH COMPANY, LTD. (JP) | 2016-06-14 | — | — | US | disclosed |
| US-20150158814-A1 | FULLERENE DERIVATIVE, AND METHOD OF PREPARING THE SAME | RICOH COMPANY, LTD. (JP) | 2015-06-11 | — | — | US | disclosed |
| US-20150158814-A1 | FULLERENE DERIVATIVE, AND METHOD OF PREPARING THE SAME | RICOH COMPANY, LTD. (JP) | 2015-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150158814-A1 | FULLERENE DERIVATIVE, AND METHOD OF PREPARING THE SAME | NCL, PFDN2, NUP50 | ACHE 2315/4885KMT2A 3512/4885MEN1 1152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.