Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | ELANE | P08246 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.36 |
| ▸ | TPMT | P51580 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16785682 | 0.91 | CYP3A4 (0.38) | CYP3A4ELANEMEN1KMT2AMAPT | |
| SCHEMBL16785680 | 0.86 | ELANE (0.39) | CYP3A4ELANEMEN1KMT2AMAPT | |
| SCHEMBL16785681 | 0.84 | ELANE (0.38) | CYP3A4ELANEMEN1KMT2AMAPT | |
| SCHEMBL16785677 | 0.82 | ACHE (0.48) | ELANEMEN1KMT2AMAPTPOLB | |
| SCHEMBL24110725 | 0.82 | LMNA (0.40) | CYP3A4ELANEMEN1KMT2AMAPT | |
| SCHEMBL16785678 | 0.81 | ELANE (0.38) | CYP3A4ELANEMEN1KMT2AMAPT | |
| SCHEMBL16785684 | 0.80 | ELANE (0.41) | ELANE | |
| SCHEMBL16785683 | 0.80 | ELANE (0.41) | ELANE | |
| SCHEMBL16785672 | 0.79 | ACHE (0.55) | CYP3A4ELANEMEN1KMT2AMAPT | |
| SCHEMBL16785671 | 0.79 | ELANE (0.42) | ELANEMAPTPOLBTDP1MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9365513-B2 | Fullerene derivative, and method of preparing the same | RICOH COMPANY, LTD. (JP) | 2016-06-14 | — | — | US | disclosed |
| US-20150158814-A1 | FULLERENE DERIVATIVE, AND METHOD OF PREPARING THE SAME | RICOH COMPANY, LTD. (JP) | 2015-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150158814-A1 | FULLERENE DERIVATIVE, AND METHOD OF PREPARING THE SAME | NCL, PFDN2, NUP50 | CYP3A4 1102/4885ELANE 1208/4885MEN1 1152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.