SCHEMBL16786158

SCHEMBL16786158

CO[Si](CCCCCC[Si](CO)(CO)CO)(OC)OC

nearest known ligand 0.39

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5419627 0.85 LMNA (0.45) LMNA
SCHEMBL5412526 0.85 LMNA (0.45) LMNA
SCHEMBL19986527 0.82 LMNA (0.30) LMNA
SCHEMBL5423906 0.82 LMNA (0.41) LMNA
SCHEMBL3792627 0.82 LMNA (0.50) LMNA
SCHEMBL399581 0.82 LMNA (0.50) LMNA
SCHEMBL396922 0.82 LMNA (0.50) LMNA
SCHEMBL20478198 0.82 LMNA (0.50) LMNA
SCHEMBL20478196 0.82 LMNA (0.50) LMNA
SCHEMBL3741069 0.82 LMNA (0.50) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10040923-B2 Room-temperature-curable organopolysiloxane composition, and moulded product comprising cured product of said room-temperature-curable organopolysiloxane composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-08-07 US disclosed
US-20170130031-A1 ROOM-TEMPERATURE-CURABLE ORGANOPOLYSILOXANE COMPOSITION, AND MOULDED PRODUCT COMPRISING CURED PRODUCT OF SAID ROOM-TEMPERATURE-CURABLE ORGANOPOLYSILOXANE COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-05-11 US disclosed
US-20170037066-A1 NOVEL BIS (ALKOXYSILYL-VINYLENE) GROUP-CONTAINING SILICON COMPOUND AND PRODUCTION METHOD OF SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-02-09 US disclosed
US-20150159039-A1 RADIATION CURABLE COMPOSITION, AND METHOD FOR PREPARING A HYBRID SOL-GEL LAYER ON A SURFACE OF A SUBSTRATE USING SAID COMPOSITION SOCOMORE (FR) 2015-06-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170037066-A1 NOVEL BIS (ALKOXYSILYL-VINYLENE) GROUP-CONTAINING SILICON COMPOUND AND PRODUCTION METHOD OF SAME ACVRL1, MSL1, HBS1L LMNA 2309/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.