Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23841258 | 0.93 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2EPHX1HPGDKMT2A | |
| SCHEMBL307675 | 0.93 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2EPHX1HPGDKMT2A | |
| SCHEMBL26660436 | 0.90 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2EPHX1HPGDKMT2A | |
| Hydrochloric Acid SCHEMBL4978162 | 0.88 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2EPHX1HPGDKMT2A | |
| SCHEMBL18536761 | 0.82 | ALDH1A1 (0.88) | ALDH1A1SMN1; SMN2EPHX1HPGDKMT2A | |
| SCHEMBL3075216 | 0.80 | EPHX1 (0.68) | ALDH1A1SMN1; SMN2EPHX1HPGDKMT2A | |
| SCHEMBL13690845 | 0.79 | SMN1; SMN2 (0.54) | ALDH1A1SMN1; SMN2EPHX1HPGDKMT2A | |
| SCHEMBL2416229 | 0.79 | SMN1; SMN2 (0.54) | ALDH1A1SMN1; SMN2EPHX1HPGDKMT2A | |
| SCHEMBL14963068 | 0.79 | SMN1; SMN2 (0.77) | ALDH1A1SMN1; SMN2EPHX1HPGDEPHX2 | |
| SCHEMBL2096794 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107863-A1 | HETEROCYCLIC COMPOUNDS AS KIT KINASE INHIBITORS | DECIPHERA PHARMACEUTICALS, LLC (US) | 2023-06-15 | — | — | WO | disclosed |
| US-9896473-B2 | Thiol compounds and the use thereof for the synthesis of modified oligonucleotides | ETABLISSEMENT FRANCAIS DU SANG (FR) | 2018-02-20 | — | — | US | disclosed |
| US-20150158964-A1 | THIOL COMPOUNDS AND THE USE THEREOF FOR THE SYNTHESIS OF MODIFIED OLIGONUCLEOTIDES | UNIVERSITE CLAUDE BERNARD LYON 1 (FR) | 2015-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150158964-A1 | THIOL COMPOUNDS AND THE USE THEREOF FOR THE SYNTHESIS OF MODIFIED OLIGONUCLEOTIDES | TST, APEX1, TMT1A | ALDH1A1 329/4885SMN1; SMN2 4558/4885EPHX1 3142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.