Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | SI | P14410 | 4/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RHOA | P61586 | 1/20 | 0.34 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1679551 | 0.87 | ALDH1A1 (0.38) | ALDH1A1HSD17B10KDM4ETP53HPGD | |
| SCHEMBL1679149 | 0.77 | CYP2C9 (0.48) | HSD17B10HPGDCYP3A4MAPTMEN1 | |
| SCHEMBL1679486 | 0.76 | CYP2C19 (0.46) | HSD17B10CYP3A4PTGS2CD274MMP9 | |
| SCHEMBL30677889 | 0.76 | CA12 (0.42) | ALDH1A1KDM4ETP53HPGDGAA | |
| SCHEMBL9838070 | 0.75 | ALDH1A1 (0.46) | ALDH1A1HSD17B10KDM4ETP53HPGD | |
| SCHEMBL7168890 | 0.72 | MEN1 (0.48) | ALDH1A1HSD17B10HPGDGAACYP3A4 | |
| SCHEMBL10715476 | 0.70 | ALDH1A1 (0.47) | ALDH1A1HSD17B10KDM4ETP53HPGD | |
| SCHEMBL10776692 | 0.70 | ALDH1A1 (0.47) | ALDH1A1HSD17B10KDM4ETP53HPGD | |
| SCHEMBL30677890 | 0.70 | ABL1 (0.44) | ALDH1A1KDM4EHPGDMAPTKMT2A | |
| SCHEMBL28518787 | 0.70 | PTGS1 (0.46) | NPSR1MEN1KMT2APTGS2CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7923573-B2 | Benzene compound having 2 or more substituents | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-04-12 | — | — | US | disclosed |
| US-20080004301-A1 | Benzene Compound Having 2 or More Substituents | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2008-01-03 | — | — | US | disclosed |
| EP-1806332-A1 | BENZENE COMPOUND HAVING 2 OR MORE SUBSTITUENTS | Daiichi Sankyo Company, Limited (JP) | 2007-07-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080004301-A1 | Benzene Compound Having 2 or More Substituents | NR1H2, NR1H3, NCOR2 | ALDH1A1 3512/4885HSD17B10 373/4885KDM4E 1970/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.