SCHEMBL30677889

SCHEMBL30677889

CCOC(=O)C(C)c1ccccc1-c1ccc(O)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.42
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CA7 P43166 2/20 0.42
CA9 Q16790 2/20 0.42
CA14 Q9ULX7 2/20 0.42
ESR1 P03372 1/20 0.42
ESR2 Q92731 1/20 0.42
ALDH2 P05091 1/20 0.42
PPARA Q07869 2/20 0.40
PPARG P37231 1/20 0.40
TSHR P16473 1/20 0.40
BACE1 P56817 1/20 0.40
TDP1 Q9NUW8 3/20 0.40
LMNA P02545 4/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
MAPT P10636 2/20 0.39
PIN1 Q13526 1/20 0.39
ABL1 P00519 1/20 0.39
ABCB1 P08183 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2392888 0.89 LMNA (0.46) PPARAPPARGTSHRTDP1LMNA
SCHEMBL30677890 0.85 ABL1 (0.44) CA12CA1CA2CA9ESR1
SCHEMBL8148942 0.80 PTGS2 (0.51) CA12CA1CA2CA9PPARA
SCHEMBL31074064 0.78 TSHR (0.53) CA12CA1CA2CA7CA9
SCHEMBL10858287 0.78 TSHR (0.53) CA12CA1CA2CA7CA9
SCHEMBL363983 0.77 TSHR (0.48) ESR1TSHRTDP1LMNASMN1; SMN2
SCHEMBL27915165 0.77 TSHR (0.43) CA12CA1CA2CA7CA9
SCHEMBL1678652 0.76 ALDH1A1 (0.40) ALDH2TSHRMAPTKMT2AALDH1A1
SCHEMBL28008252 0.76 NLRP3 (0.50) TSHRTDP1LMNASMN1; SMN2PIN1
SCHEMBL10914468 0.76 PPARA (0.42) PPARAPPARGLMNASMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11767452-B2 Curable composition, especially as crystallizing rubber to substrate bonding primer HENKEL AG & CO. KGAA (DE) 2023-09-26 US disclosed