Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | CCR9 | P51686 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16789474 | 0.87 | KDM4E (0.41) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL15335218 | 0.87 | ALDH1A1 (0.38) | KDM4EALDH1A1KMT2AJAK2JAK1 | |
| SCHEMBL16789475 | 0.80 | KCNH2 (0.51) | — | |
| SCHEMBL15335138 | 0.77 | KDM4E (0.38) | KDM4EALDH1A1MEN1KMT2AJAK2 | |
| SCHEMBL15335222 | 0.77 | KDM4E (0.38) | KDM4EALDH1A1JAK2JAK1JAK3 | |
| SCHEMBL8177614 | 0.76 | KDM4E (0.43) | KDM4EALDH1A1MEN1KMT2AJAK2 | |
| SCHEMBL15335145 | 0.73 | JAK2 (0.37) | KDM4EALDH1A1LMNAJAK2JAK1 | |
| SCHEMBL15334966 | 0.73 | CNR2 (0.48) | KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL16293902 | 0.72 | HDAC6 (0.41) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL30765666 | 0.71 | KDM4E (0.51) | KDM4EALDH1A1JAK2JAK1JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9315499-B2 | Cytomegalovirus inhibitor compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2016-04-19 | — | — | US | disclosed |
| US-20150158861-A1 | CYTOMEGALOVIRUS INHIBITOR COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150158861-A1 | CYTOMEGALOVIRUS INHIBITOR COMPOUNDS | CCNT1, CDKN1A, FOXM1 | KDM4E 3052/4885ALDH1A1 3564/4885MEN1 182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.