Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 8/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
| ▸ | CTRC | Q99895 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31558583 | 0.89 | KDM4E (0.51) | KDM4EALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6087779 | 0.86 | CTRC (0.52) | KDM4EALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL30765660 | 0.86 | KDM4E (0.51) | KDM4EALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL30765953 | 0.83 | ALDH1A1 (0.42) | KDM4EALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7476393 | 0.82 | ALDH1A1 (0.47) | KDM4EALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6245424 | 0.80 | ELANE (0.49) | KDM4EALDH1A1ELANEMAPT | |
| SCHEMBL11768659 | 0.79 | KDM4E (0.50) | KDM4EALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL23460649 | 0.79 | ELANE (0.47) | KDM4EALDH1A1ELANECMA1CTRC | |
| SCHEMBL6178282 | 0.79 | ELANE (0.51) | KDM4EALDH1A1ELANE | |
| SCHEMBL6242996 | 0.78 | NPC1 (0.49) | KDM4EALDH1A1CYP2C19ELANEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| CN-119768164-A | Pharmaceutical compounds for treating complement-mediated disorders | 阿雷克森制药公司 | 2025-04-04 | — | — | CN | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |