SCHEMBL16789934

SCHEMBL16789934

N#Cc1cccc(N2CCN(c3cccc(C#N)c3)C2=C2N(c3cccc(C#N)c3)CCN2c2cccc(C#N)c2)c1

nearest known ligand 0.59

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 7/20 0.59
DRD3 P35462 6/20 0.59
NSD2 O96028 1/20 0.55
KCNH2 Q12809 3/20 0.50
ALOX5 P09917 1/20 0.49
NOTUM Q6P988 2/20 0.47
DRD4 P21917 2/20 0.45
FADS1 O60427 2/20 0.45
C1S P09871 1/20 0.45
GRM2 Q14416 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16705239 0.81 NSD2 (0.64) DRD2DRD3NSD2KCNH2ALOX5
SCHEMBL15800697 0.80 DRD2 (0.79) DRD2DRD3NSD2ALOX5NOTUM
SCHEMBL3951237 0.78 NSD2 (0.56) DRD2DRD3NSD2KCNH2ALOX5
SCHEMBL29809089 0.77 DRD2 (0.74) DRD2DRD3NSD2ALOX5NOTUM
SCHEMBL3537217 0.77 DRD2 (0.74) DRD2DRD3NSD2ALOX5NOTUM
SCHEMBL3551042 0.76 ALOX5 (0.59) DRD2DRD3NSD2KCNH2ALOX5
SCHEMBL4468086 0.76 DRD2 (0.72) DRD2DRD3NSD2ALOX5NOTUM
SCHEMBL16789935 0.75 KDM4E (0.52) KCNH2NOTUM
SCHEMBL19693904 0.75 NSD2 (0.54) DRD2DRD3NSD2KCNH2ALOX5
SCHEMBL29519746 0.75 NSD2 (0.54) DRD2DRD3NSD2KCNH2ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10541260-B2 Organic photoelectric conversion element, optical area sensor, imaging device, and imaging apparatus CANON KABUSHIKI KAISHA (JP) 2020-01-21 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed
US-9842997-B2 Organic light emitting element and display device CANON KABUSHIKI KAISHA (JP) 2017-12-12 US disclosed
US-20150162545-A1 ORGANIC LIGHT EMITTING ELEMENT AND DISPLAY DEVICE CANON KABUSHIKI KAISHA (JP) 2015-06-11 US disclosed