Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.33 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.33 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2418344 | 0.82 | TSHR (0.47) | GABRA1GABRB2EPHX1XDHPNMT | |
| SCHEMBL10159908 | 0.79 | GABRA1 (0.41) | GABRA1GABRB2EPHX1PTGS2PTGS1 | |
| SCHEMBL3021690 | 0.77 | GABRA1 (0.48) | GABRA1GABRB2EPHX1XDHPNMT | |
| SCHEMBL11652715 | 0.76 | GABRA1 (0.42) | GABRA1GABRB2EPHX1PTGS2PTGS1 | |
| SCHEMBL15452636 | 0.73 | HTR2A (0.36) | GABRA1GABRB2XDHPNMTHTR2A | |
| SCHEMBL11511762 | 0.73 | SKP2 (0.53) | GABRA1GABRB2EPHX1XDHPNMT | |
| SCHEMBL24385301 | 0.72 | GABRA1 (0.44) | GABRA1GABRB2EPHX1XDHPNMT | |
| SCHEMBL9199000 | 0.72 | CYP3A4 (0.61) | GABRA1GABRB2EPHX1PNMTTSHR | |
| SCHEMBL20223460 | 0.72 | ALDH1A1 (0.45) | GABRA1GABRB2EPHX1XDHPNMT | |
| SCHEMBL2416692 | 0.72 | GABRA1 (0.44) | GABRA1GABRB2EPHX1XDHPNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3080077-A1 | TRIPODAL NITRATE RECEPTOR | University Of Oregon (US) | 2016-10-19 | — | — | EP | disclosed |
| WO-2015089271-A1 | TRIPODAL NITRATE RECEPTOR | UNIVERSITY OF OREGON (US) | 2015-06-18 | — | — | WO | disclosed |