Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.58 |
| ▸ | NOD1 | Q9Y239 | 6/20 | 0.55 |
| ▸ | NOD2 | Q9HC29 | 5/20 | 0.55 |
| ▸ | CCR2 | P41597 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16792457 | 1.00 | ALOX5 (0.58) | ALOX5NOD1NOD2CCR2ALDH1A1 | |
| SCHEMBL16792452 | 1.00 | ALOX5 (0.58) | ALOX5NOD1NOD2CCR2ALDH1A1 | |
| SCHEMBL10003531 | 0.93 | ALDH1A1 (0.48) | ALOX5NOD1NOD2CCR2ALDH1A1 | |
| SCHEMBL20291498 | 0.93 | ALDH1A1 (0.48) | ALOX5NOD1NOD2CCR2ALDH1A1 | |
| SCHEMBL10003527 | 0.93 | ALDH1A1 (0.48) | ALOX5NOD1NOD2CCR2ALDH1A1 | |
| SCHEMBL10003556 | 0.91 | ALOX5 (0.46) | ALOX5NOD1NOD2ALDH1A1LMNA | |
| SCHEMBL10003553 | 0.91 | ALOX5 (0.46) | ALOX5NOD1NOD2ALDH1A1LMNA | |
| SCHEMBL16188508 | 0.91 | ALOX5 (0.46) | ALOX5NOD1NOD2ALDH1A1LMNA | |
| SCHEMBL28195762 | 0.88 | ALOX5 (0.60) | ALOX5NOD1NOD2CCR2ALDH1A1 | |
| SCHEMBL10003655 | 0.87 | ALOX5 (0.43) | ALOX5NOD1NOD2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3080098-A1 | INHIBITORS OF BRUTON'S TYROSINE KINASE | F. Hoffmann-La Roche AG (CH) | 2016-10-19 | — | — | EP | disclosed |
| WO-2015086636-A1 | INHIBITORS OF BRUTON'S TYROSINE KINASE | F. HOFFMANN-LA ROCHE AG (CH) | 2015-06-18 | — | — | WO | disclosed |