SCHEMBL1679320

SCHEMBL1679320

N[C@@H](Cc1ccc(OC(=O)[C@@H](N)CO)cc1)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 5/20 0.56
PTPN1 P18031 2/20 0.55
PTGS1 P23219 3/20 0.54
ALPI P09923 1/20 0.54
PKM P14618 1/20 0.54
XIAP P98170 1/20 0.54
ITGB3 P05106 1/20 0.54
ITGA2B P08514 1/20 0.54
TPH1 P17752 2/20 0.48
GRB2 P62993 1/20 0.48
ALOX15 P16050 3/20 0.47
HIF1A Q16665 3/20 0.47
KDM4E B2RXH2 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
USP2 O75604 1/20 0.47
EGFR P00533 1/20 0.47
LCK P06239 1/20 0.47
FYN P06241 1/20 0.47
ADORA3 P0DMS8 1/20 0.47
HTR2A P28223 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Serine SCHEMBL9073599 0.91 SLC7A5 (0.61) SLC7A5PTPN1PTGS1ALPIPKM
SCHEMBL2464010 0.88 SLC7A5 (0.53) SLC7A5PTPN1PTGS1ALPIPKM
Phenylalanine SCHEMBL5608077 0.88 SLC7A5 (0.69) SLC7A5PTPN1PTGS1ALPIPKM
Phenylalanine SCHEMBL5699042 0.88 SLC7A5 (0.69) SLC7A5PTPN1PTGS1ALPIPKM
SCHEMBL1003560 0.88 SLC7A5 (0.69) SLC7A5PTPN1PTGS1ALPIPKM
SCHEMBL60228 0.86 SLC7A5 (0.73) SLC7A5PTPN1PTGS1ALPIPKM
SCHEMBL9120090 0.86 SLC7A5 (0.54) SLC7A5PTPN1PTGS1ALPIPKM
SCHEMBL11676390 0.86 SLC7A5 (0.73) SLC7A5PTPN1PTGS1ALPIPKM
SCHEMBL10978818 0.86 SLC7A5 (0.73) SLC7A5PTPN1PTGS1ALPIPKM
SCHEMBL1667022 0.86 SLC7A5 (0.73) SLC7A5PTPN1PTGS1ALPIPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024047497-A1 TREATMENTS FOR PRURIGO NODULARIS Galderma Holding SA (CH) 2024-03-07 WO disclosed
CN-115369461-A Platinum group metal electroplating solution complexing agent composition for medical and electronic wearable equipment 永星化工(上海)有限公司 2022-11-22 CN disclosed
CN-114431342-A Protein amino acid pet food for promoting development and detection method thereof 弘煋科技(北京)有限公司 2022-05-06 CN disclosed
US-20190192691-A1 REGULATED BIOCIRCUIT SYSTEMS OBSIDIAN THERAPEUTICS, INC. 2019-06-27 US disclosed
EP-3443001-A2 REGULATED BIOCIRCUIT SYSTEMS Obsidian Therapeutics, Inc. (US) 2019-02-20 EP disclosed
WO-2017180587-A2 REGULATED BIOCIRCUIT SYSTEMS OBSIDIAN THERAPEUTICS, INC. (US) 2017-10-19 WO disclosed
EP-3102611-A1 HUMANIZED BETA-AMYLOID BINDING MOLECULES AND USES THEREOF Cangene Corporation (CA) 2016-12-14 EP disclosed
WO-2015113169-A1 HUMANIZED BETA-AMYLOID BINDING MOLECULES AND USES THEREOF CNJ HOLDINGS, INC. (CA) 2015-08-06 WO disclosed
EP-2307051-A2 NOTCH-BINDING AGENTS AND ANTAGONISTS AND METHODS OF USE THEREOF OncoMed Pharmaceuticals, Inc. (US) 2011-04-13 EP disclosed
WO-2010005566-A2 NOTCH-BINDING AGENTS AND ANTAGONISTS AND METHODS OF USE THEREOF ONCOMED PHARMACEUTICALS, INC. (US) 2010-01-14 WO disclosed
US-20030166224-A1 18232, a novel dual specificity phosphatase and uses therefor MILLENNIUM PHARMACEUTICALS, INC., A DELAWARE CORPORATION 2003-09-04 US disclosed
WO-2001064911-A9 18232, A DUAL SPECIFICITY PHOSPHATASE MILLENNIUM PHARM INC (US) 2003-02-06 WO disclosed
EP-1259625-A2 18232, A DUAL SPECIFICITY PHOSPHATASE Millennium Pharmaceuticals, Inc. (US) 2002-11-27 EP disclosed
US-6420153-B1 NUCLEOTIDE SEQUENCES CODING ENZYMATIC POLYPEPTIDES FOR USE IN THE DIAGNOSIS, TREATMENT AND PREVENTION OF BLOOD DISORDERS AND LEUKEMIAS MILLENNIUM PHARMACEUTICALS, INC. 2002-07-16 US disclosed
WO-2001064911-A2 18232, A DUAL SPECIFICITY PHOSPHATASE MILLENNIUM PHARMACEUTICALS, INC. (US) 2001-09-07 WO disclosed
CN-1066331-C Oral medicinal liquor prepared from Armilariella tabescens WANG WENXIAN (CN) 2001-05-30 CN disclosed
WO-2000049889-A1 ANIMAL FEED SUPPLEMENT FOR THE NUTRITIONAL ENRICHMENT OF ANIMAL PRODUCE BARTLETT GRAIN PTY. LTD. (AU) 2000-08-31 WO disclosed
CN-1227501-A Long-acting drugs and pharmaceutical compositions comprising them YEDA RES & DEV (IL) 1999-09-01 CN disclosed
CN-1217916-A Oral medicinal liquor prepared from Armilariella tabescens WANG WENXIAN (CN) 1999-06-02 CN disclosed
WO-1998024432-A2 USE OF INDOLINONE COMPOUNDS AS MODULATORS OF PROTEIN KINASES SUGEN, INC. (US) 1998-06-11 WO disclosed