SCHEMBL167933

SCHEMBL167933

Cc1c(C)c2ccccc2c2ccccc12

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 7/20 0.53
TSHR P16473 5/20 0.46
HSD17B10 Q99714 3/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
MAPK1 P28482 2/20 0.46
HPGD P15428 2/20 0.46
ATM Q13315 2/20 0.46
CYP3A4 P08684 2/20 0.46
HIF1A Q16665 2/20 0.46
CASP1 P29466 1/20 0.46
RAB9A P51151 1/20 0.46
CASP7 P55210 1/20 0.46
CYP2A6 P11509 6/20 0.46
NPC1 O15118 1/20 0.46
HSP90AA1 P07900 1/20 0.46
ACHE P22303 2/20 0.44
GPR3 P46089 2/20 0.43
AHR P35869 1/20 0.43
ALDH1A1 P00352 4/20 0.43
HPRT1 P00492 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL357443 0.92 CYP1A2 (0.53) CYP1A2TSHRHSD17B10L3MBTL1MAPK1
SCHEMBL29660297 0.92 CYP1A2 (0.53) CYP1A2TSHRHSD17B10L3MBTL1MAPK1
Ammonia Solution, Strong SCHEMBL2263911 0.89 CYP1A2 (0.50) CYP1A2TSHRHSD17B10L3MBTL1MAPK1
SCHEMBL28539881 0.89 CYP1A2 (0.50) CYP1A2TSHRHSD17B10L3MBTL1MAPK1
SCHEMBL29379467 0.88 CYP1A2 (0.56) CYP1A2TSHRHSD17B10L3MBTL1MAPK1
SCHEMBL377040 0.88 CYP1A2 (0.56) CYP1A2TSHRHSD17B10L3MBTL1MAPK1
Hydrazine SCHEMBL394386 0.86 CYP1A2 (0.47) CYP1A2TSHRHSD17B10L3MBTL1MAPK1
SCHEMBL4514863 0.85 CYP1A2 (0.53) CYP1A2TSHRHSD17B10L3MBTL1MAPK1
SCHEMBL7506419 0.81 TSHR (0.56) CYP1A2TSHRHSD17B10L3MBTL1MAPK1
SCHEMBL164133 0.81 HSD17B10 (0.45) CYP1A2TSHRHSD17B10L3MBTL1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 517 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111303360-B Polymer containing piperidine tertiary amine group, anion exchange polymer, and preparation methods and applications thereof 惠州市亿纬新能源研究院 2023-03-03 CN claimed
CN-111303360-A Polymer containing piperidine tertiary amine group, anion exchange polymer, and preparation methods and applications thereof 惠州市亿纬新能源研究院 2020-06-19 CN claimed
US-9120715-B2 Alkylation of aromatic substrates TOTAL PETROCHEMICALS FRANCE (FR) 2015-09-01 US claimed
US-20140206917-A1 Alkylation of Aromatic Substrates TOTAL PETROCHEMICALS FRANCE (FR) 2014-07-24 US claimed
CN-102216215-B Process for making alkylaromatics using EMM-12 EXXONMOBIL CHEM PATENTS INC 2014-03-26 CN claimed
CN-102105397-B Process for making alkylaromatics using EMM-13 EXXON MOBIL CHEM PATENTS INC 2014-02-05 CN claimed
CN-101679882-B Improved process for the preparation of alkylaromatic compounds EXXON MOBIL CHEM PATENTS INC 2013-09-11 CN claimed
US-8466333-B2 Process of making alkylaromatics using EMM-12 EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-06-18 US claimed
EP-2134815-B1 IMPROVED ALKYLAROMATIC PRODUCTION PROCESS EXXONMOBIL CHEM PATENTS INC (US) 2013-05-01 EP claimed
US-8217213-B2 Hydroalkylation of aromatic compounds using EMM-12 EXXONMOBIL CHEMICAL PATENTS INC. (US) 2012-07-10 US claimed
US-20110077438-A1 Hydroalkylation of Aromatic Compounds Using EMM-13 EXXONMOBIL CHEMICAL PATENTS INC. 2011-03-31 US claimed
US-20110071329-A1 Hydroalkylation of Aromatic Compounds Using EMM-12 EXXONMOBIL CHEMICAL PATENTS INC. 2011-03-24 US claimed
WO-2010014404-A1 PROCESS OF MAKING ALKYLAROMATICS USING EMM-13 EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-02-04 WO claimed
WO-2010014402-A1 HYDROALKYLATION OF AROMATIC COMPOUNDS USING EMM-12 EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-02-04 WO claimed
WO-2010014401-A1 HYDROALKYLATION OF AROMATIC COMPOUNDS USING EMM-13 EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-02-04 WO claimed
WO-2010014405-A1 PROCESS OF MAKING ALKYLAROMATICS USING EMM-12 EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-02-04 WO claimed
EP-2134815-A1 IMPROVED ALKYLAROMATIC PRODUCTION PROCESS Exxonmobil Chemical Patents Inc. A Corporation Of The State Of Delaware (US) 2009-12-23 EP claimed
WO-2008097737-A1 IMPROVED ALKYLAROMATIC PRODUCTION PROCESS EXXONMOBIL CHEMICAL PATENTS INC. A CORPORATION OF THE STATE OF DELAWARE (US) 2008-08-14 WO claimed
US-20080194897-A1 Alkylaromatic Production Process EXXONMOBIL CHEMICAL PATENTS INC. 2008-08-14 US claimed
US-5073655-A Alkylation of aromatic hydrocarbon with aromatic alklating hal ide, alcohol or olefin, a mixed oxide of silica or germania wi th alumina, boria, iron oxide or gallium oxide MOBIL OIL CORP. (US) 1991-12-17 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110077438-A1 Hydroalkylation of Aromatic Compounds Using EMM-13 HM13, SEC13, ALK CYP1A2 515/4885TSHR 4617/4885HSD17B10 1269/4885
US-20110071329-A1 Hydroalkylation of Aromatic Compounds Using EMM-12 ADAM12, CASP12, RBM12 CYP1A2 983/4885TSHR 4682/4885HSD17B10 1189/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.