Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | SNCA | P37840 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 4/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31182 | 0.95 | SNCA (0.59) | LMNAKDM4ESNCAESR1ESR2 | |
| SCHEMBL1920792 | 0.93 | SNCA (0.58) | LMNAKDM4ESNCAESR1ESR2 | |
| Hydrochloric Acid SCHEMBL28144301 | 0.93 | SNCA (0.58) | LMNAKDM4ESNCAESR1ESR2 | |
| SCHEMBL461801 | 0.93 | SNCA (0.61) | LMNAKDM4ESNCAMEN1KMT2A | |
| Phenol SCHEMBL28318935 | 0.88 | LMNA (0.60) | LMNAKDM4ESNCAESR1ESR2 | |
| Paraben SCHEMBL1146606 | 0.88 | SNCA (0.54) | LMNAKDM4ESNCAESR1ESR2 | |
| SCHEMBL175786 | 0.87 | SNCA (0.67) | LMNAKDM4ESNCAESR1ESR2 | |
| SCHEMBL2346908 | 0.86 | CYP3A4 (0.61) | LMNAKDM4ESNCAMEN1KMT2A | |
| SCHEMBL9717267 | 0.86 | SNCA (0.55) | LMNAKDM4ESNCAMEN1KMT2A | |
| SCHEMBL1222875 | 0.85 | SNCA (0.51) | LMNAKDM4ESNCAESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0311692-B1 | NOVEL ALKANOYL ESTER COMPOUNDS, INTERMEDIATES THEREFOR, AND PROCESSES FOR THEIR PREPARATION | NIPPON MINING COMPANY LIMITED (JP) | 1992-07-08 | — | — | EP | claimed |
| EP-0311692-A1 | NOVEL ALKANOYL ESTER COMPOUNDS, INTERMEDIATES THEREFOR, AND PROCESSES FOR THEIR PREPARATION | NIPPON MINING COMPANY LIMITED (JP) | 1989-04-19 | — | — | EP | claimed |
| JP-62087556-A | — | — | None | — | — | JP | disclosed |
| JP-60023476-A | — | — | None | — | — | JP | disclosed |
| JP-1233262-A | — | — | None | — | — | JP | disclosed |
| US-7923573-B2 | Benzene compound having 2 or more substituents | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-04-12 | — | — | US | disclosed |
| US-20080255111-A1 | Tissue Factor Production Inhibitor | SANKYO COMPANY LIMITED (JP) | 2008-10-16 | — | — | US | disclosed |
| US-20080004301-A1 | Benzene Compound Having 2 or More Substituents | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2008-01-03 | — | — | US | disclosed |
| EP-1806332-A1 | BENZENE COMPOUND HAVING 2 OR MORE SUBSTITUENTS | Daiichi Sankyo Company, Limited (JP) | 2007-07-11 | — | — | EP | disclosed |
| EP-1764075-A1 | TISSUE FACTOR PRODUCTION INHIBITOR | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |
| US-5891359-A | FLUOROTRIESTERAROMATIC COMPOUND FOR LIQUID CRYSTALS | SHOWA SHELL SEKIYU KABUSHIKI KAISHA (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0164814-B1 | LIQUID CRYSTALLINE ESTER COMPOUNDS AND MIXTURES THEREOF | Chisso Corporation (JP) | 1990-11-28 | — | — | EP | disclosed |
| JP-H01233262-A | FLUOROALKOXYBIPHENBYLCARBOXYLIC ACID DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | SHARP CORP | 1989-09-19 | — | — | JP | disclosed |
| US-4834907-A | STABLE, HIGH RESPONSE RATE | CHISSO CORPORATION (JP) | 1989-05-30 | — | — | US | disclosed |
| EP-0311692-A1 | NOVEL ALKANOYL ESTER COMPOUNDS, INTERMEDIATES THEREFOR, AND PROCESSES FOR THEIR PREPARATION | NIPPON MINING COMPANY LIMITED (JP) | 1989-04-19 | — | — | EP | disclosed |
| US-4778621-A | Ester compound | CHISSO CORPORATION (JP) | 1988-10-18 | — | — | US | disclosed |
| US-4689176-A | AROMATIC ESTER COMPOUND | CHISSO CORPORATION (JP) | 1987-08-25 | — | — | US | disclosed |
| JP-S6287556-A | ESTER COMPOUND | CHISSO CORP | 1987-04-22 | — | — | JP | disclosed |
| EP-0164814-A2 | Liquid crystalline ester compounds and mixtures thereof | Chisso Corporation (JP) | 1985-12-18 | — | — | EP | disclosed |
| JP-S6023476-A | 4-(SUBSTITUTED CARBONYLOXY)BIPHENYLYL-4'-CARBOXYLIC ACID ALKYL ESTER | CHISSO CORP | 1985-02-06 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255111-A1 | Tissue Factor Production Inhibitor | PTAFR, PLAT, TFPI | LMNA 2091/4885KDM4E 4805/4885SNCA 1498/4885 |
| US-20080004301-A1 | Benzene Compound Having 2 or More Substituents | NR1H2, NR1H3, NCOR2 | LMNA 3203/4885KDM4E 1970/4885SNCA 3884/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.