SCHEMBL1920792

SCHEMBL1920792

C=CCOC(=O)c1ccc(O)cc1.[NaH]

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SNCA P37840 1/20 0.58
ESR1 P03372 4/20 0.56
CA12 O43570 3/20 0.56
CA1 P00915 3/20 0.56
CA2 P00918 3/20 0.56
CA7 P43166 3/20 0.56
CA9 Q16790 3/20 0.56
CA14 Q9ULX7 3/20 0.56
ESR2 Q92731 2/20 0.56
MEN1 O00255 1/20 0.56
KMT2A Q03164 1/20 0.56
CYP3A4 P08684 1/20 0.55
ALDH1A1 P00352 4/20 0.53
TSHR P16473 3/20 0.53
CHRM1 P11229 1/20 0.53
SLC6A2 P23975 1/20 0.53
KDR P35968 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
KDM4E B2RXH2 2/20 0.52
HSD17B10 Q99714 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31182 0.98 SNCA (0.59) SNCAESR1CA12CA1CA2
Hydrochloric Acid SCHEMBL28144301 0.96 SNCA (0.58) SNCAESR1CA12CA1CA2
SCHEMBL1679462 0.93 LMNA (0.58) SNCAESR1CA12CA1CA2
Paraben SCHEMBL1146606 0.91 SNCA (0.54) SNCAESR1CA12CA1CA2
Phenol SCHEMBL28318935 0.91 LMNA (0.60) SNCAESR1CA12CA1CA2
SCHEMBL175786 0.90 SNCA (0.67) SNCAESR1CA12CA1CA2
SCHEMBL1222875 0.89 SNCA (0.51) SNCAESR1CA12CA1CA2
SCHEMBL461801 0.85 SNCA (0.61) SNCAMEN1KMT2ACYP3A4ALDH1A1
SCHEMBL17386391 0.85 SNCA (0.61) SNCAESR1CA12CA1CA2
Benzyl Alcohol SCHEMBL23391584 0.85 LMNA (0.60) SNCAESR1CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5155808-A None JP disclosed
US-20230125630-A1 POLYPHOSPHAZENES, METHODS OF MAKING, AND USES THEREOF UNIV MARYLAND (US) 2023-04-27 US disclosed
US-11472927-B2 Polyphosphazenes, methods of making, and uses thereof UNIVERSITY OF MARYLAND, COLLEGE PARK (US) 2022-10-18 US disclosed
US-20180327550-A1 POLYPHOSPHAZENES, METHODS OF MAKING, AND USES THEREOF UNIVERSITY OF MARYLAND, COLLEGE PARK 2018-11-15 US disclosed
EP-3377560-A1 POLYPHOSPHAZENES, METHODS OF MAKING, AND USES THEREOF University of Maryland, College Park (US) 2018-09-26 EP disclosed
US-20160377620-A1 COMBINATION HEPATITIS C VIRUS ANTIGEN AND ANTIBODY DETECTION METHOD ABBOTT LABORATORIES 2016-12-29 US disclosed
US-9470686-B2 Combination hepatitis C virus antigen and antibody detection method ABBOTT LABORATORIES (US) 2016-10-18 US disclosed
EP-2064551-B1 COMBINATION HEPATITIS C VIRUS ANTIGEN AND ANTIBODY DETECTION METHOD ABBOTT LAB (US) 2015-12-09 EP disclosed
EP-2910949-A1 Combination hepatitis C virus antigen and antibody detection method Abbott Laboratories (US) 2015-08-26 EP disclosed
US-20150177242-A1 COMBINATION HEPATITIS C VIRUS ANTIGEN AND ANTIBODY DETECTION METHOD ABBOTT LABORATORIES 2015-06-25 US disclosed
EP-0634016-A4 ASSAY VERIFICATION CONTROL FOR ANALYTICAL METHODS. ABBOTT LAB (US) 1997-06-04 EP disclosed
US-5635406-A Stabilized standards and calibrators containing rapamycin and tacrolimus bound to anti-rapamycin and anti-tacrolimus antibodies ABBOTT LABORATORIES (US) 1997-06-03 US disclosed
WO-1996041184-A1 STABILIZED STANDARDS AND CALIBRATORS ABBOTT LABORATORIES (US) 1996-12-19 WO disclosed
EP-0634016-A1 ASSAY VERIFICATION CONTROL FOR ANALYTICAL METHODS ABBOTT LABORATORIES (US) 1995-01-18 EP disclosed
WO-1994024568-A1 STABLE AQUEOUS FK506 STANDARDS ABBOTT LABORATORIES (US) 1994-10-27 WO disclosed
US-5338684-A Stable aqueous FK506 standards ABBOTT LABORATORIES (US) 1994-08-16 US disclosed
US-5266721-A Process for preparing the pure enantiomers of lifibrol and its alkyl esters KLINGE PHARMA GMBH (DE) 1993-11-30 US disclosed
US-5266721-A Process for preparing the pure enantiomers of lifibrol and its alkyl esters KLINGE PHARMA GMBH (DE) 1993-11-30 US disclosed
WO-1993020443-A1 ASSAY VERIFICATION CONTROL FOR ANALYTICAL METHODS ABBOTT LABORATORIES (US) 1993-10-14 WO disclosed
JP-H05155808-A PRODUCTION OF PURE ENANTIOMER OF 4(4-(4'TERT-BUTYL PHENYL)-2HYDROXYBUTOXY) BENZOIC ACID AND ITS ALKYLESTER KLINGE PHARM GMBH & CO 1993-06-22 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230125630-A1 POLYPHOSPHAZENES, METHODS OF MAKING, AND USES THEREOF PHOSPHO1, PLCG2, PLCG1 SNCA 3841/4885ESR1 3224/4885CA12 154/4885
US-20180327550-A1 POLYPHOSPHAZENES, METHODS OF MAKING, AND USES THEREOF PHOSPHO1, PLCG2, PLCG1 SNCA 3841/4885ESR1 3224/4885CA12 154/4885
US-11472927-B2 Polyphosphazenes, methods of making, and uses thereof PHOSPHO1, PLCG2, PLCG1 SNCA 3841/4885ESR1 3224/4885CA12 154/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.