Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 16/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 15/20 | 0.53 |
| ▸ | HTR2A | P28223 | 14/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.50 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12305651 | 0.84 | MEN1 (0.67) | SLC6A4KCNH2HTR2AMEN1MAPT | |
| SCHEMBL51173 | 0.81 | CYP3A4 (0.67) | SLC6A4KCNH2MEN1MAPTKMT2A | |
| SCHEMBL13881914 | 0.80 | SLC6A4 (0.58) | SLC6A4KCNH2HTR2ASLC6A2SLC6A3 | |
| SCHEMBL17715198 | 0.79 | TYR (0.58) | MEN1MAPTKMT2ACYP3A4ALOX15 | |
| SCHEMBL2569349 | 0.79 | SLC6A4 (0.56) | SLC6A4KCNH2HTR2ACYP3A4IDO1 | |
| SCHEMBL29875226 | 0.79 | SLC6A4 (0.56) | SLC6A4KCNH2HTR2ACYP3A4IDO1 | |
| Hydrochloric Acid SCHEMBL3591332 | 0.78 | HTT (0.59) | SLC6A4KCNH2HTR2AMEN1KMT2A | |
| SCHEMBL18588940 | 0.78 | SLC6A4 (0.55) | SLC6A4KCNH2HTR2ASLC6A2SLC6A3 | |
| SCHEMBL21494282 | 0.78 | SLC6A4 (0.47) | SLC6A4KCNH2HTR2ASLC6A2SLC6A3 | |
| SCHEMBL14020589 | 0.78 | TRPA1 (0.48) | SLC6A4KCNH2HTR2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015086693-A1 | PYRAZOLOPYRIMIDIN-2-YL DERIVATIVES AS JAK INHIBITORS | ALMIRALL, S.A. (ES) | 2015-06-18 | — | — | WO | disclosed |