Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.52 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1384166 | 0.84 | HPGD (0.49) | HPGDHIF1AALOX15KMT2AMEN1 | |
| SCHEMBL1384164 | 0.84 | HPGD (0.49) | HPGDHIF1AALOX15KMT2AMEN1 | |
| SCHEMBL17330349 | 0.83 | HPGD (0.47) | HPGDLMNAPOLBCNR1PLAAT3 | |
| SCHEMBL7405242 | 0.82 | HPGD (0.49) | HPGDKMT2AMEN1LMNAMAPT | |
| SCHEMBL17330402 | 0.82 | HPGD (0.46) | HPGDKMT2AMEN1SMN1; SMN2POLB | |
| SCHEMBL3529974 | 0.81 | HPGD (0.67) | HPGDKMT2AMEN1HTTLMNA | |
| SCHEMBL5654926 | 0.81 | HPGD (0.48) | HPGDKMT2ACNR1PLAAT3PLAAT5 | |
| SCHEMBL1418003 | 0.79 | HIF1A (0.59) | HPGDHIF1AALOX15KMT2AMEN1 | |
| SCHEMBL19376791 | 0.79 | HPGD (0.49) | HPGDKMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL13840658 | 0.77 | HIF1A (0.62) | HPGDHIF1AALOX15KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015086693-A1 | PYRAZOLOPYRIMIDIN-2-YL DERIVATIVES AS JAK INHIBITORS | ALMIRALL, S.A. (ES) | 2015-06-18 | — | — | WO | disclosed |