Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.45 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.45 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.45 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5654926 | 0.86 | HPGD (0.48) | HPGDCNR1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL3529974 | 0.83 | HPGD (0.67) | HPGDCNR1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL6924316 | 0.83 | P2RX7 (0.48) | MAPTALDH1A1KMT2AMEN1TDP1 | |
| SCHEMBL17330349 | 0.82 | HPGD (0.47) | HPGDCNR1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL16795265 | 0.82 | HPGD (0.52) | HPGDCNR1MAPTPLAAT3PLAAT5 | |
| SCHEMBL17330402 | 0.81 | HPGD (0.46) | HPGDCNR1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL19376791 | 0.81 | HPGD (0.49) | HPGDCNR1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL6920257 | 0.79 | IDO1 (0.55) | HPGDMAPTALDH1A1KDM4EKMT2A | |
| SCHEMBL20563681 | 0.78 | HPGD (0.47) | HPGDCNR1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL10537631 | 0.75 | IDO1 (0.43) | HPGDMAPTALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002057225-A2 | THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 2002-07-25 | — | — | WO | disclosed |