Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 6/20 | 0.47 |
| ▸ | ACHE | P22303 | 6/20 | 0.47 |
| ▸ | BACE1 | P56817 | 6/20 | 0.47 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | QDPR | P09417 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.35 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20767080 | 0.82 | BCHE (0.50) | BCHEACHEBACE1PABPC1KDM4E | |
| SCHEMBL16795184 | 0.81 | BCHE (0.52) | BCHEACHEBACE1PABPC1CARM1 | |
| SCHEMBL27709142 | 0.78 | BCHE (0.49) | BCHEACHEBACE1PABPC1KDM4E | |
| SCHEMBL29546328 | 0.72 | BCHE (0.64) | BCHEACHEBACE1KDM4EALDH1A1 | |
| SCHEMBL20766753 | 0.72 | BCHE (0.64) | BCHEACHEBACE1KDM4EALDH1A1 | |
| SCHEMBL12074561 | 0.71 | ACHE (0.50) | BCHEACHEBACE1KDM4EALDH1A1 | |
| SCHEMBL20780551 | 0.71 | BCHE (0.50) | BCHEACHEBACE1KDM4EALDH1A1 | |
| SCHEMBL12074147 | 0.71 | BCHE (0.50) | BCHEACHEBACE1KDM4EALDH1A1 | |
| SCHEMBL20766411 | 0.71 | MEN1 (0.46) | BCHEACHEBACE1KDM4EALDH1A1 | |
| SCHEMBL30523669 | 0.71 | MEN1 (0.46) | BCHEACHEBACE1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015086693-A1 | PYRAZOLOPYRIMIDIN-2-YL DERIVATIVES AS JAK INHIBITORS | ALMIRALL, S.A. (ES) | 2015-06-18 | — | — | WO | disclosed |