Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 5/20 | 0.49 |
| ▸ | ACHE | P22303 | 5/20 | 0.49 |
| ▸ | BACE1 | P56817 | 5/20 | 0.49 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20767080 | 0.81 | BCHE (0.50) | BCHEACHEBACE1PABPC1MAPK14 | |
| SCHEMBL4240966 | 0.80 | ADRB2 (0.37) | BCHEACHEBACE1SLC2A1DRD4 | |
| SCHEMBL16795184 | 0.80 | BCHE (0.52) | BCHEACHEBACE1PABPC1POLB | |
| SCHEMBL5533747 | 0.80 | DRD4 (0.50) | BCHEACHEBACE1DRD4 | |
| SCHEMBL16795384 | 0.78 | BCHE (0.47) | BCHEACHEBACE1PABPC1SLC2A1 | |
| SCHEMBL16222287 | 0.72 | CARM1 (0.56) | — | |
| SCHEMBL20766459 | 0.72 | ACKR3 (0.47) | BCHEACHEBACE1KDM4EL3MBTL1 | |
| SCHEMBL20766753 | 0.71 | BCHE (0.64) | BCHEACHEBACE1KDM4EACKR3 | |
| SCHEMBL29546328 | 0.71 | BCHE (0.64) | BCHEACHEBACE1KDM4EACKR3 | |
| SCHEMBL20780551 | 0.70 | BCHE (0.50) | BCHEACHEBACE1KDM4EACKR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101128460-A | Tricyclic delta-opioid modulators | JANSSEN PHARMACEUTICA NV (BE) | 2008-02-20 | — | — | CN | disclosed |