Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 7/20 | 0.50 |
| ▸ | BACE1 | P56817 | 7/20 | 0.50 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.48 |
| ▸ | BCHE | P06276 | 6/20 | 0.48 |
| ▸ | MGLL | Q99685 | 2/20 | 0.46 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.45 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.44 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL377906 | 0.86 | DRD4 (0.64) | DRD4ACHEBACE1TEAD1BCHE | |
| SCHEMBL12803076 | 0.85 | CARM1 (0.59) | DRD4SIGMAR1ACHEBACE1TEAD1 | |
| SCHEMBL20570422 | 0.82 | TEAD1 (0.71) | DRD4SIGMAR1ACHEBACE1TEAD1 | |
| SCHEMBL4080791 | 0.81 | FABP6 (0.60) | DRD4ACHEBACE1BCHECARM1 | |
| SCHEMBL5680610 | 0.78 | ALDH1A1 (0.59) | SSTR3 | |
| SCHEMBL1189971 | 0.77 | ACHE (0.60) | DRD4ACHEBACE1TEAD1BCHE | |
| SCHEMBL16269315 | 0.77 | ACHE (0.60) | DRD4ACHEBACE1TEAD1BCHE | |
| SCHEMBL16464327 | 0.77 | TDP1 (0.50) | ACHEBACE1BCHE | |
| SCHEMBL3712791 | 0.76 | ACHE (0.60) | DRD4SIGMAR1ACHEBACE1TEAD1 | |
| SCHEMBL6103122 | 0.75 | MEN1 (0.60) | SIGMAR1ACHEBACE1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015086693-A1 | PYRAZOLOPYRIMIDIN-2-YL DERIVATIVES AS JAK INHIBITORS | ALMIRALL, S.A. (ES) | 2015-06-18 | — | — | WO | disclosed |