Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.58 |
| ▸ | RECQL | P46063 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.52 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6258932 | 1.00 | HTT (0.58) | HTTRECQLMAPTKMT2AMEN1 | |
| SCHEMBL1218 | 0.94 | HTT (0.65) | HTTRECQLMAPTKMT2AMEN1 | |
| SCHEMBL1643 | 0.94 | HTT (0.65) | HTTRECQLMAPTKMT2AMEN1 | |
| SCHEMBL30269691 | 0.94 | HTT (0.65) | HTTRECQLMAPTKMT2AMEN1 | |
| SCHEMBL29364482 | 0.94 | HTT (0.65) | HTTRECQLMAPTKMT2AMEN1 | |
| SCHEMBL9486033 | 0.94 | HTT (0.65) | HTTRECQLMAPTKMT2AMEN1 | |
| SCHEMBL29496911 | 0.80 | — | — | |
| SCHEMBL1699 | 0.80 | — | — | |
| SCHEMBL8039612 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL4897791 | 0.79 | ALDH1A1 (0.63) | HTTKMT2ACYP1A2CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015087343-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF NILOTINIB AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | LAURUS LABS PRIVATE LIMITED (IN) | 2015-06-18 | — | — | WO | disclosed |