Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.65 |
| ▸ | RECQL | P46063 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.58 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.58 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1643 | 1.00 | HTT (0.65) | HTTRECQLMAPTKMT2AMEN1 | |
| SCHEMBL9486033 | 1.00 | HTT (0.65) | HTTRECQLMAPTKMT2AMEN1 | |
| SCHEMBL30269691 | 1.00 | HTT (0.65) | HTTRECQLMAPTKMT2AMEN1 | |
| SCHEMBL1218 | 1.00 | HTT (0.65) | HTTRECQLMAPTKMT2AMEN1 | |
| SCHEMBL6258932 | 0.94 | HTT (0.58) | HTTRECQLMAPTKMT2AMEN1 | |
| SCHEMBL16795470 | 0.94 | HTT (0.58) | HTTRECQLMAPTKMT2AMEN1 | |
| SCHEMBL7368742 | 0.83 | MAPK1 (0.60) | HTTMAPTKMT2AMEN1CYP1A2 | |
| SCHEMBL7368740 | 0.83 | MAPK1 (0.60) | HTTMAPTKMT2AMEN1CYP1A2 | |
| SCHEMBL10036804 | 0.81 | CYP1A1 (0.63) | MAPTKMT2AMEN1CYP1A2CYP1A1 | |
| SCHEMBL166048 | 0.81 | CYP1A1 (0.63) | MAPTKMT2AMEN1CYP1A2CYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025231152-A1 | COMPOUNDS AND METHODS FOR RESTORING BETA-ADRENERGIC RECEPTOR FUNCTION | THE CLEVELAND CLINIC FOUNDATION (US) | 2025-11-06 | — | — | WO | disclosed |
| CN-119859377-A | Polyacetal resin composition | 旭化成株式会社 | 2025-04-22 | — | — | CN | disclosed |
| CN-117836596-A | Temperature indicator manufacturing system and temperature indicator manufacturing method | 株式会社日立产机系统 | 2024-04-05 | — | — | CN | disclosed |
| CN-110872279-B | High-yield synthesis method of nilotinib | 安徽峆一药业股份有限公司 | 2023-09-08 | — | — | CN | disclosed |
| CN-111542736-B | Temperature detecting material and estimation system for temperature deviation time using the same | 株式会社日立产机系统 | 2023-08-29 | — | — | CN | disclosed |
| EP-4045494-A1 | SYNTHESIS OF 6-METHYL-N1-(4-(PYRIDIN-3-YL)PYRIMIDIN-2-YL)BENZENE-1,3-DIAMINE | Esco Aster Pte. Ltd. (SG) | 2022-08-24 | — | — | EP | disclosed |
| CN-114585615-A | Synthesis of 6-methyl-N1- (4- (pyridin-3-yl) pyrimidin-2-yl) benzene-1, 3-diamine | 新加坡艺思高艾斯特生物科技有限公司 | 2022-06-03 | — | — | CN | disclosed |
| CN-110114647-B | Temperature detection material, manufacturing method thereof and application of temperature detection material | 株式会社日立产机系统 | 2022-04-22 | — | — | CN | disclosed |
| CN-110078706-B | Imatinib derivative and preparation method and application thereof | 浙江师范大学 | 2022-02-01 | — | — | CN | disclosed |