Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 17/20 | 0.88 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.60 |
| ▸ | MAOA | P21397 | 1/20 | 0.57 |
| ▸ | IDO1 | P14902 | 1/20 | 0.57 |
| ▸ | AGXT | P21549 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16795550 | 0.93 | MAOB (1.00) | MAOBMRGPRX4MAOA | |
| SCHEMBL7917245 | 0.90 | MAOB (0.77) | MAOBMRGPRX4MAOA | |
| SCHEMBL4404036 | 0.88 | MAOB (1.00) | MAOBMRGPRX4MAOAIDO1AGXT | |
| SCHEMBL28075228 | 0.87 | MAOB (0.75) | MAOB | |
| SCHEMBL16795567 | 0.85 | MAOB (0.79) | MAOBMRGPRX4MAOA | |
| SCHEMBL16710547 | 0.84 | MAOB (0.71) | MAOBMRGPRX4IDO1AGXT | |
| SCHEMBL13462942 | 0.83 | MAOB (0.69) | MAOBMRGPRX4IDO1AGXT | |
| SCHEMBL13263642 | 0.82 | MAOB (0.79) | MAOBMRGPRX4IDO1AGXT | |
| SCHEMBL29666660 | 0.82 | MAOB (1.00) | MAOBMRGPRX4MAOA | |
| SCHEMBL73864 | 0.82 | MAOB (1.00) | MAOBMRGPRX4MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015087094-A1 | NEW ARYLALKENYLPROPARGYLAMINE DERIVATIVES EXHIBITING NEUROPROTECTIVE ACTION FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | SEMMELWEIS EGYETEM (HU) | 2015-06-18 | — | — | WO | disclosed |