Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 16/20 | 0.77 |
| ▸ | APP | P05067 | 1/20 | 0.55 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16795652 | 0.90 | MAOB (0.88) | MAOBMRGPRX4MAOA | |
| SCHEMBL16795550 | 0.87 | MAOB (1.00) | MAOBAPPMRGPRX4MAOA | |
| SCHEMBL28075228 | 0.87 | MAOB (0.75) | MAOBAPP | |
| SCHEMBL5987976 | 0.81 | MAOB (0.76) | MAOBAPPMRGPRX4ABCB1MAOA | |
| SCHEMBL91264 | 0.81 | MAOB (0.67) | MAOBAPPMRGPRX4ABCB1 | |
| SCHEMBL7917111 | 0.81 | MAOB (0.62) | MAOBAPPMRGPRX4ABCB1 | |
| SCHEMBL29775530 | 0.81 | MAOB (0.57) | MAOBAPPMRGPRX4ABCB1 | |
| SCHEMBL4404036 | 0.80 | MAOB (1.00) | MAOBMRGPRX4MAOA | |
| SCHEMBL13332739 | 0.80 | MAOB (0.70) | MAOBAPPMRGPRX4ABCB1 | |
| SCHEMBL8265677 | 0.80 | MAOB (0.77) | MAOBAPPMRGPRX4ABCB1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6225352-B1 | USEFUL AS AGENTS IN THE TREATMENT OF CANCER, ALZHEIMERS DISEASE, THROMBOSIS, INFLAMMATORY DISEASES, AND BACTERIAL RESISTANCE | WARNER-LAMBERT COMPANY | 2001-05-01 | — | — | US | disclosed |
| WO-1998006691-A2 | LOW MOLECULAR WEIGHT DENDRITIC COMPOUNDS AS PHARMACEUTICAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1998-02-19 | — | — | WO | disclosed |