SCHEMBL73864

SCHEMBL73864

Brc1cccc(OCc2ccccc2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MAOB P27338 13/20 1.00
MRGPRX4 Q96LA9 1/20 0.67
MAOA P21397 2/20 0.59
CYP4F2 P78329 1/20 0.59
CYP4A11 Q02928 1/20 0.59
BCHE P06276 1/20 0.59
NPC1 O15118 1/20 0.57
ALDH1A1 P00352 1/20 0.57
RAB9A P51151 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
NR4A2 P43354 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29666660 1.00 MAOB (1.00) MAOBMRGPRX4MAOACYP4F2CYP4A11
SCHEMBL17978716 0.98 MAOB (0.96) MAOBMRGPRX4MAOACYP4F2CYP4A11
SCHEMBL4404036 0.90 MAOB (1.00) MAOBMRGPRX4MAOANPC1ALDH1A1
SCHEMBL12746077 0.90 MAOB (0.81) MAOBMRGPRX4MAOACYP4F2CYP4A11
Bicarbonate SCHEMBL8552113 0.89 MAOB (0.79) MAOBMRGPRX4MAOACYP4F2CYP4A11
Bicarbonate SCHEMBL8552114 0.89 MAOB (0.79) MAOBMRGPRX4MAOACYP4F2CYP4A11
SCHEMBL13469158 0.89 MAOB (0.82) MAOBMRGPRX4MAOA
SCHEMBL24628659 0.86 MAOB (0.74) MAOBMRGPRX4CYP4F2CYP4A11
SCHEMBL1268719 0.86 MAOB (0.81) MAOBMAOACYP4F2CYP4A11BCHE
SCHEMBL10046165 0.84 MAOB (0.72) MAOBMRGPRX4MAOARAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 591 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120136886-A PDE4 inhibitor with pyranonaphthyridone skeleton and preparation method and application thereof 中山大学 2025-06-13 CN claimed
WO-2025093057-A1 METHOD FOR PREPARING METARAMINOL BITARTRATE 武汉武药制药有限公司 2025-05-08 WO claimed
CN-119930447-A Preparation method of meta-hydroxylamine bitartrate 武汉武药制药有限公司 2025-05-06 CN claimed
CN-118899116-B Curve heating fire-resistant power cable and preparation method thereof 广州澳通电线电缆有限公司 2025-04-04 CN claimed
CN-119504454-A Synthesis process of meta-hydroxylamine bitartrate 海南卓科制药有限公司 2025-02-25 CN claimed
CN-119080710-A Meta-hydroxylamine bitartrate impurity, synthesis method and application 上海现代哈森(商丘)药业有限公司 2024-12-06 CN claimed
CN-118899116-A Curve heating novel fire-resistant power cable and preparation method thereof 广州澳通电线电缆有限公司 2024-11-05 CN claimed
CN-115960003-A Synthesis method of meta-hydroxylamine bitartrate 中科苏州药物研究院 2023-04-14 CN claimed
CN-104016879-B Dibenzoyl amine compound with anti-tumor activity and its preparation method and application XI'AN JIAOTONG UNIVERSITY (CN) 2016-02-24 CN claimed
CN-103980153-B Dibenzoyl amine compound with anti-tumor activity and its preparation method and application XI'AN JIAOTONG UNIVERSITY (CN) 2016-01-20 CN claimed
CN-104016879-A Diphenyl amide compound with anti-tumor activity as well as preparation method and application of diphenyl amide compound UNIV XI AN JIAOTONG 2014-09-03 CN claimed
CN-103980153-A Biphenyl amide compound with antitumor activity as well as preparation method and application thereof UNIV XI AN JIAOTONG 2014-08-13 CN claimed
US-12638613-B2 Ophthalmic lenses and their manufacture by in-mold modification JOHNSON & JOHNSON VISION CARE, INC. (US) 2026-05-26 US disclosed
EP-4408852-B1 ANTHRAQUINONE-FUNCTIONALIZED POLYMERIZATION INITIATORS AND THEIR USE IN THE MANUFACTURE OF OPHTHALMIC LENSES JOHNSON & JOHNSON VISION CARE (US) 2026-04-08 EP disclosed
US-12577251-B2 Modulators of the sigma-2 receptor and their method of use Temple University—Of the Commonwealth System of Higher Education (US) 2026-03-17 US disclosed
US-20260021192-A1 PROTEINS HAVING A COVALENT WARHEAD TOPAZ THERAPEUTICS INC (US) 2026-01-22 US disclosed
US-4214084-A Ethanopyrrolo[1,2-b]isoquinolines STERLING DRUG INC. (US) 1980-07-22 US disclosed
US-4179567-A 2-Aryltropane compounds STERLING DRUG INC. (US) 1979-12-18 US disclosed
US-3992536-A SEDATIVES AND MUSCLE RELAXANTS BOEHRINGER INGELHEIM GMBH (DT) 1976-11-16 US disclosed
US-3931185-A SEDATIVES, MUSCLE RELAXANT BOEHRINGER INGELHEIM GMBH (DT) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12638613-B2 Ophthalmic lenses and their manufacture by in-mold modification UACA, AXL, CRYZ MAOB 1746/4885MRGPRX4 4100/4885MAOA 838/4885
US-20260021192-A1 PROTEINS HAVING A COVALENT WARHEAD RIOX2, ORC3, DCLRE1A MAOB 3262/4885MRGPRX4 3804/4885MAOA 3534/4885
US-12577251-B2 Modulators of the sigma-2 receptor and their method of use SIGMAR1, CHRNA6, NR3C2 MAOB 1032/4885MRGPRX4 416/4885MAOA 1510/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.