Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10517345 | 0.95 | NFKB1 (0.35) | NFKB1NFKB2RELA | |
| SCHEMBL11224811 | 0.79 | NFKB1 (0.37) | NFKB1NFKB2RELA | |
| SCHEMBL27540198 | 0.63 | NFKB1 (0.31) | NFKB1NFKB2RELA | |
| SCHEMBL11766874 | 0.62 | NFKB1 (0.41) | NFKB1NFKB2RELA | |
| SCHEMBL4021367 | 0.62 | DNTT (0.42) | NFKB1NFKB2RELA | |
| SCHEMBL8025115 | 0.62 | ALDH1A1 (0.34) | — | |
| SCHEMBL8018146 | 0.62 | ALDH1A1 (0.34) | — | |
| SCHEMBL9755515 | 0.61 | DNTT (0.41) | NFKB1NFKB2RELA | |
| SCHEMBL27315472 | 0.58 | ALDH1A1 (0.37) | — | |
| SCHEMBL10992975 | 0.57 | TSHR (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015087094-A1 | NEW ARYLALKENYLPROPARGYLAMINE DERIVATIVES EXHIBITING NEUROPROTECTIVE ACTION FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | SEMMELWEIS EGYETEM (HU) | 2015-06-18 | — | — | WO | disclosed |