Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.51 |
| ▸ | CA2 | P00918 | 3/20 | 0.51 |
| ▸ | CA9 | Q16790 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28788080 | 0.87 | CA12 (0.55) | CA12CA2CA9NPC1RAB9A | |
| SCHEMBL29855934 | 0.85 | NPC1 (0.66) | CA12CA2CA9NPC1RAB9A | |
| SCHEMBL4444737 | 0.85 | NPC1 (0.66) | CA12CA2CA9NPC1RAB9A | |
| SCHEMBL16796021 | 0.84 | NPC1 (0.53) | NPC1RAB9AHPGDLMNAMAPT | |
| SCHEMBL4300998 | 0.84 | NPC1 (0.57) | NPC1RAB9AHPGDLMNAMAPT | |
| SCHEMBL14059469 | 0.82 | CA12 (0.54) | CA12CA2CA9NPC1RAB9A | |
| SCHEMBL29429098 | 0.82 | CA12 (0.54) | CA12CA2CA9NPC1RAB9A | |
| SCHEMBL4308501 | 0.82 | NPC1 (0.44) | CA12CA2CA9NPC1RAB9A | |
| SCHEMBL28684394 | 0.82 | CA12 (0.54) | CA12CA2CA9NPC1RAB9A | |
| SCHEMBL16796019 | 0.79 | AKR1C3 (0.48) | NPC1RAB9AMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3080189-B1 | POLYMERIC MATERIALS | VICTREX MFG LTD (GB) | 2020-02-12 | — | — | EP | disclosed |
| US-20160304667-A1 | POLYMERIC MATERIALS | VICTREX MANUFACTURING LIMITED (GB) | 2016-10-20 | — | — | US | disclosed |
| EP-3080189-A1 | POLYMERIC MATERIALS | Victrex Manufacturing Limited (GB) | 2016-10-19 | — | — | EP | disclosed |
| WO-2015087059-A1 | POLYMERIC MATERIALS | VICTREX MANUFACTURING LIMITED (GB) | 2015-06-18 | — | — | WO | disclosed |