Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.66 |
| ▸ | RAB9A | P51151 | 1/20 | 0.66 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29855934 | 1.00 | NPC1 (0.66) | NPC1RAB9AAKR1C3MAPTGAA | |
| SCHEMBL13703668 | 0.89 | AKR1C3 (0.58) | NPC1RAB9AAKR1C3MAPTFFAR1 | |
| SCHEMBL4300998 | 0.89 | NPC1 (0.57) | NPC1RAB9AAKR1C3MAPTGAA | |
| SCHEMBL16796021 | 0.89 | NPC1 (0.53) | NPC1RAB9AAKR1C3MAPTGAA | |
| SCHEMBL17224539 | 0.89 | KMT2A (0.53) | NPC1RAB9AAKR1C3MAPTGAA | |
| SCHEMBL16796015 | 0.85 | CA12 (0.51) | NPC1RAB9AAKR1C3MAPTGAA | |
| SCHEMBL2256468 | 0.82 | NPC1 (0.72) | NPC1RAB9AMAPTFFAR1ALDH1A1 | |
| SCHEMBL29479413 | 0.82 | NPC1 (0.72) | NPC1RAB9AMAPTFFAR1ALDH1A1 | |
| SCHEMBL16796019 | 0.82 | AKR1C3 (0.48) | NPC1RAB9AAKR1C3MAPTGAA | |
| SCHEMBL4308501 | 0.80 | NPC1 (0.44) | NPC1RAB9AAKR1C3GAAFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7265198-B2 | Sulfonated polyarylenethioethersulfone polymer and copolymer compositions | UNIVERSITY OF DAYTON (US) | 2007-09-04 | — | — | US | claimed |
| EP-1699849-A1 | SULFONATED POLYARYLENETHIOETHERSULFONE POLYMER AND COPOLYMER COMPOSITIONS | UNIVERSITY OF DAYTON (US) | 2006-09-13 | — | — | EP | claimed |
| US-20050165213-A1 | Sulfonated polyarylenethioethersulfone polymer compositions | UNIVERSITY OF DAYTON | 2005-07-28 | — | — | US | claimed |
| WO-2005059007-A1 | SULFONATED POLYARYLENETHIOETHERSULFONE POLYMER AND COPOLYMER COMPOSITIONS | UNIVERSITY OF DAYTON (US) | 2005-06-30 | — | — | WO | claimed |
| US-11840607-B1 | Cross-linkable thermoplastics, and processes of making and using same | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2023-12-12 | — | — | US | disclosed |
| CN-110467524-B | Method for preparing 1, 2-dicarbonyl compound through photocatalytic oxidation reaction | 中国科学院理化技术研究所 | 2022-08-30 | — | — | CN | disclosed |
| CN-111333680-B | Phosphine ligand and preparation method and application thereof | 万华化学集团股份有限公司 | 2022-08-05 | — | — | CN | disclosed |
| CN-111333680-A | Phosphine ligand and preparation method and application thereof | 万华化学集团股份有限公司 | 2020-06-26 | — | — | CN | disclosed |
| US-7582722-B1 | Phenylethynylbenzophenone-endcapped hyperbranched poly(arylene-ether-ketone-imides) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2009-09-01 | — | — | US | disclosed |
| US-7265198-B2 | Sulfonated polyarylenethioethersulfone polymer and copolymer compositions | UNIVERSITY OF DAYTON (US) | 2007-09-04 | — | — | US | disclosed |
| EP-1699849-A1 | SULFONATED POLYARYLENETHIOETHERSULFONE POLYMER AND COPOLYMER COMPOSITIONS | UNIVERSITY OF DAYTON (US) | 2006-09-13 | — | — | EP | disclosed |
| US-20050165213-A1 | Sulfonated polyarylenethioethersulfone polymer compositions | UNIVERSITY OF DAYTON | 2005-07-28 | — | — | US | disclosed |
| WO-2005059007-A1 | SULFONATED POLYARYLENETHIOETHERSULFONE POLYMER AND COPOLYMER COMPOSITIONS | UNIVERSITY OF DAYTON (US) | 2005-06-30 | — | — | WO | disclosed |
| EP-0842212-A4 | IMIDE OLIGOMERS AND CO-OLIGOMERS CONTAINING PENDENT PHENYLETHYNYL GROUPS AND POLYMERS THEREFROM | NASA (US) | 1998-10-14 | — | — | EP | disclosed |
| EP-0842212-A1 | IMIDE OLIGOMERS AND CO-OLIGOMERS CONTAINING PENDENT PHENYLETHYNYL GROUPS AND POLYMERS THEREFROM | NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 1998-05-20 | — | — | EP | disclosed |
| WO-1997006200-A1 | IMIDE OLIGOMERS AND CO-OLIGOMERS CONTAINING PENDENT PHENYLETHYNYL GROUPS AND POLYMERS THEREFROM | NATIONAL AERONAUTICS & SPACE ADMINISTRATION (US) | 1997-02-20 | — | — | WO | disclosed |
| US-5599993-A | USED FOR ENDCAPPING POLYIMIDES WITH EXCELLENT SOLVENT AND CHEMICAL RESISTANCE, HIGH STRENGTH AND MODULUS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 1997-02-04 | — | — | US | disclosed |
| US-5412066-A | Adhesives | THER UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 1995-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11840607-B1 | Cross-linkable thermoplastics, and processes of making and using same | MTCL3, DUOX2, DUOX1 | NPC1 4852/4885RAB9A 3851/4885AKR1C3 2717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.