Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29855934 | 0.82 | NPC1 (0.66) | AKR1C3GAAMAPTNPC1RAB9A | |
| SCHEMBL4444737 | 0.82 | NPC1 (0.66) | AKR1C3GAAMAPTNPC1RAB9A | |
| SCHEMBL16796021 | 0.82 | NPC1 (0.53) | AKR1C3GAAMAPTNPC1RAB9A | |
| SCHEMBL333008 | 0.79 | AKR1C3 (0.61) | AKR1C3GAAMAPTNPC1RAB9A | |
| SCHEMBL29433447 | 0.79 | AKR1C3 (0.61) | AKR1C3GAAMAPTNPC1RAB9A | |
| SCHEMBL4300998 | 0.79 | NPC1 (0.57) | AKR1C3GAAMAPTNPC1RAB9A | |
| SCHEMBL31317034 | 0.79 | NPC1 (0.66) | GAAMAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL16796015 | 0.79 | CA12 (0.51) | AKR1C3GAAMAPTNPC1RAB9A | |
| SCHEMBL64069 | 0.76 | AKR1C3 (0.57) | AKR1C3GAAMAPTALDH1A1ATM | |
| SCHEMBL1331831 | 0.76 | AKR1C3 (0.57) | AKR1C3GAAMAPTALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3080189-B1 | POLYMERIC MATERIALS | VICTREX MFG LTD (GB) | 2020-02-12 | — | — | EP | disclosed |
| US-20160304667-A1 | POLYMERIC MATERIALS | VICTREX MANUFACTURING LIMITED (GB) | 2016-10-20 | — | — | US | disclosed |
| EP-3080189-A1 | POLYMERIC MATERIALS | Victrex Manufacturing Limited (GB) | 2016-10-19 | — | — | EP | disclosed |
| WO-2015087059-A1 | POLYMERIC MATERIALS | VICTREX MANUFACTURING LIMITED (GB) | 2015-06-18 | — | — | WO | disclosed |