Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CPT2 | P23786 | 1/20 | 0.32 |
| ▸ | ACLY | P53396 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ITGAV | P06756 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15539909 | 1.00 | MAPT (0.36) | MAPTHSP90AA1GPR55LMNAMAPK1 | |
| SCHEMBL15539822 | 1.00 | MAPT (0.36) | MAPTHSP90AA1GPR55LMNAMAPK1 | |
| SCHEMBL15539622 | 0.81 | GABRA1 (0.36) | MAPTHSP90AA1GPR55LMNAMAPK1 | |
| SCHEMBL15538386 | 0.81 | GABRA1 (0.36) | MAPTHSP90AA1GPR55LMNAMAPK1 | |
| SCHEMBL16795793 | 0.81 | GABRA1 (0.36) | MAPTHSP90AA1GPR55LMNAMAPK1 | |
| SCHEMBL15538966 | 0.79 | KIF11 (0.41) | MAPTHSP90AA1GPR55LMNAMAPK1 | |
| SCHEMBL15539304 | 0.79 | KCNN4 (0.44) | LMNAMAPK1ALDH1A1KMT2AMEN1 | |
| SCHEMBL15540080 | 0.79 | KIF11 (0.41) | MAPTHSP90AA1GPR55LMNAMAPK1 | |
| SCHEMBL15540225 | 0.79 | KCNN4 (0.44) | LMNAMAPK1ALDH1A1KMT2AMEN1 | |
| SCHEMBL16795807 | 0.79 | KIF11 (0.41) | MAPTHSP90AA1GPR55LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3079685-A1 | SULFAMATE DERIVATIVE COMPOUNDS FOR USE IN TREATING OR ALLEVIATING PAIN | Bio-Pharm Solutions Co., Ltd. (KR) | 2016-10-19 | — | — | EP | disclosed |
| WO-2015088273-A9 | SULFAMATE DERIVATIVE COMPOUNDS FOR USE IN TREATING OR ALLEVIATING PAIN | BIO-PHARM SOLUTIONS, CO., LTD. (KR) | 2015-08-06 | — | — | WO | disclosed |
| WO-2015088273-A1 | SULFAMATE DERIVATIVE COMPOUNDS FOR USE IN TREATING OR ALLEVIATING PAIN | BIO-PHARM SOLUTIONS, CO., LTD. (KR) | 2015-06-18 | — | — | WO | disclosed |