Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.65 |
| ▸ | NPC1 | O15118 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | TP53 | P04637 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 13/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13381577 | 0.86 | KMT2A (0.75) | RAB9ANPC1SMN1; SMN2TP53KMT2A | |
| SCHEMBL10892540 | 0.82 | KMT2A (0.56) | RAB9ANPC1SMN1; SMN2TP53KMT2A | |
| SCHEMBL14130698 | 0.81 | KMT2A (0.72) | RAB9ANPC1SMN1; SMN2TP53KMT2A | |
| Furostilbestrol SCHEMBL2109382 | 0.81 | KMT2A (0.68) | RAB9ANPC1SMN1; SMN2TP53KMT2A | |
| SCHEMBL16797440 | 0.79 | KMT2A (0.74) | SMN1; SMN2KMT2AMAPTALDH1A1HSD17B10 | |
| SCHEMBL5943067 | 0.79 | KMT2A (0.76) | RAB9ANPC1SMN1; SMN2KMT2AMAPT | |
| SCHEMBL25054068 | 0.79 | KMT2A (0.74) | RAB9ANPC1SMN1; SMN2TP53KMT2A | |
| SCHEMBL12647712 | 0.79 | KMT2A (0.66) | RAB9ANPC1SMN1; SMN2KMT2AMAPT | |
| SCHEMBL13802894 | 0.78 | KMT2A (0.64) | RAB9ANPC1SMN1; SMN2TP53KMT2A | |
| SCHEMBL9047691 | 0.78 | KMT2A (0.64) | RAB9ANPC1SMN1; SMN2TP53KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3079680-A2 | COMPOSITIONS AND METHODS FOR TREATING, PREVENTING AND DIAGNOSING CANCER AND OTHER PROLIFERATIVE DISORDERS | Angiogenex, Inc. (US) | 2016-10-19 | — | — | EP | disclosed |
| WO-2015089495-A2 | COMPOSITIONS AND METHODS FOR TREATING, PREVENTING AND DIAGNOSING CANCER AND OTHER PROLIFERATIVE DISORDERS | ANGIOGENEX, INC. (US) | 2015-06-18 | — | — | WO | disclosed |