Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 16/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.72 |
| ▸ | NPC1 | O15118 | 3/20 | 0.72 |
| ▸ | RAB9A | P51151 | 3/20 | 0.72 |
| ▸ | TP53 | P04637 | 1/20 | 0.72 |
| ▸ | RECQL | P46063 | 1/20 | 0.72 |
| ▸ | PKM | P14618 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13381577 | 0.91 | KMT2A (0.75) | KMT2ASMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL5943067 | 0.83 | KMT2A (0.76) | KMT2ASMN1; SMN2NPC1RAB9APKM | |
| SCHEMBL25054068 | 0.83 | KMT2A (0.74) | KMT2ASMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL13802894 | 0.82 | KMT2A (0.64) | KMT2ASMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL9047691 | 0.82 | KMT2A (0.64) | KMT2ASMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL12591803 | 0.81 | KMT2A (0.63) | KMT2ASMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL16797441 | 0.81 | RAB9A (0.65) | KMT2ASMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL13791553 | 0.81 | KMT2A (0.85) | KMT2ASMN1; SMN2RECQLPKMMAPT | |
| SCHEMBL6382860 | 0.81 | KMT2A (0.71) | KMT2ASMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL25054116 | 0.79 | KMT2A (0.60) | KMT2ASMN1; SMN2NPC1RAB9APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102946882-B | Phenylalamine derivatives and as the purposes of non-peptide GLP-1-1 receptor modulators | ARGUSINA, INC. (US) | 2016-05-18 | — | — | CN | disclosed |
| CN-102946882-A | Phenylalanine derivatives and their use as non-peptide glp-1 receptor modulators | ARGUSINA INC | 2013-02-27 | — | — | CN | disclosed |
| US-20080182851-A1 | ACETYLENE DERIVATIVES AS STEAROYL COA DESATURASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2008-07-31 | — | — | US | disclosed |
| US-20080182851-A1 | ACETYLENE DERIVATIVES AS STEAROYL COA DESATURASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2008-07-31 | — | — | US | disclosed |
| WO-2008062276-A2 | ACETYLENE DERIVATIVES AS STEAROYL COA DESATURASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (US) | 2008-05-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080182851-A1 | ACETYLENE DERIVATIVES AS STEAROYL COA DESATURASE INHIBITORS | SCD, SCD5, ACACA | KMT2A 2996/4885SMN1; SMN2 2065/4885NPC1 103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.