Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 12/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 4/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | FPR1 | P21462 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27906644 | 0.83 | KMT2A (0.63) | KMT2AHSD17B10ALDH1A1TSHRPOLB | |
| SCHEMBL16797441 | 0.79 | RAB9A (0.65) | KMT2AHSD17B10SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL31321696 | 0.78 | ALDH1A1 (0.54) | KMT2ASMN1; SMN2ALDH1A1POLBKDM4E | |
| SCHEMBL10892540 | 0.77 | KMT2A (0.56) | KMT2AHSD17B10SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL31321700 | 0.77 | L3MBTL1 (0.61) | KMT2AHSD17B10SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL859237 | 0.76 | NPC1 (0.61) | KMT2AHSD17B10SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL7701028 | 0.76 | KMT2A (1.00) | KMT2AHSD17B10ALDH1A1TSHRPOLB | |
| SCHEMBL2380676 | 0.76 | L3MBTL1 (0.63) | KMT2AALDH1A1POLBKDM4EGAA | |
| SCHEMBL28204092 | 0.75 | NPC1 (0.60) | KMT2AHSD17B10SMN1; SMN2ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL27676954 | 0.75 | NPC1 (0.60) | KMT2AHSD17B10SMN1; SMN2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3079680-A2 | COMPOSITIONS AND METHODS FOR TREATING, PREVENTING AND DIAGNOSING CANCER AND OTHER PROLIFERATIVE DISORDERS | Angiogenex, Inc. (US) | 2016-10-19 | — | — | EP | disclosed |
| WO-2015089495-A2 | COMPOSITIONS AND METHODS FOR TREATING, PREVENTING AND DIAGNOSING CANCER AND OTHER PROLIFERATIVE DISORDERS | ANGIOGENEX, INC. (US) | 2015-06-18 | — | — | WO | disclosed |