Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.79 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.77 |
| ▸ | TSHR | P16473 | 3/20 | 0.77 |
| ▸ | MEN1 | O00255 | 3/20 | 0.77 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.73 |
| ▸ | RAB9A | P51151 | 1/20 | 0.71 |
| ▸ | HTT | P42858 | 2/20 | 0.69 |
| ▸ | GLA | P06280 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 3/20 | 0.65 |
| ▸ | STAT6 | P42226 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13832067 | 0.92 | KMT2A (0.75) | HSD17B10KMT2AALOX15SMN1; SMN2ALDH1A1 | |
| SCHEMBL4368602 | 0.90 | KMT2A (0.75) | HSD17B10KMT2AALOX15SMN1; SMN2ALDH1A1 | |
| SCHEMBL3889633 | 0.87 | MAPT (0.82) | HSD17B10KMT2AALOX15SMN1; SMN2ALDH1A1 | |
| SCHEMBL15983278 | 0.87 | KMT2A (0.74) | HSD17B10KMT2AALOX15SMN1; SMN2ALDH1A1 | |
| SCHEMBL15983277 | 0.86 | ALDH1A1 (0.70) | HSD17B10KMT2AALOX15SMN1; SMN2ALDH1A1 | |
| SCHEMBL15983290 | 0.82 | MAPT (0.82) | HSD17B10KMT2AALOX15SMN1; SMN2ALDH1A1 | |
| SCHEMBL18559063 | 0.81 | PTK2 (0.80) | KMT2ASMN1; SMN2ALDH1A1KDM4EMEN1 | |
| SCHEMBL14478848 | 0.80 | KDM4E (0.81) | HSD17B10KMT2AALOX15SMN1; SMN2ALDH1A1 | |
| SCHEMBL13831372 | 0.79 | KMT2A (0.71) | HSD17B10KMT2AALOX15SMN1; SMN2ALDH1A1 | |
| SCHEMBL13832070 | 0.79 | ALDH1A1 (0.83) | HSD17B10KMT2ASMN1; SMN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3079680-A2 | COMPOSITIONS AND METHODS FOR TREATING, PREVENTING AND DIAGNOSING CANCER AND OTHER PROLIFERATIVE DISORDERS | Angiogenex, Inc. (US) | 2016-10-19 | — | — | EP | disclosed |
| WO-2015089495-A2 | COMPOSITIONS AND METHODS FOR TREATING, PREVENTING AND DIAGNOSING CANCER AND OTHER PROLIFERATIVE DISORDERS | ANGIOGENEX, INC. (US) | 2015-06-18 | — | — | WO | disclosed |