Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.82 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.82 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.81 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.81 |
| ▸ | POLB | P06746 | 3/20 | 0.81 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.80 |
| ▸ | USP2 | O75604 | 3/20 | 0.69 |
| ▸ | HPGD | P15428 | 3/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.69 |
| ▸ | HTT | P42858 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | CASP1 | P29466 | 1/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15983290 | 0.92 | MAPT (0.82) | MAPTNPSR1HSD17B10KDM4EPOLB | |
| SCHEMBL13832070 | 0.92 | ALDH1A1 (0.83) | MAPTNPSR1HSD17B10KDM4EPOLB | |
| SCHEMBL18559153 | 0.90 | MAPT (1.00) | MAPTNPSR1HSD17B10KDM4EPOLB | |
| SCHEMBL22046603 | 0.90 | MAPT (0.79) | MAPTNPSR1HSD17B10KDM4EPOLB | |
| SCHEMBL15983283 | 0.89 | MAPT (0.78) | MAPTNPSR1HSD17B10KDM4EPOLB | |
| SCHEMBL18559259 | 0.89 | MAPT (1.00) | MAPTNPSR1HSD17B10KDM4EPOLB | |
| SCHEMBL18559074 | 0.89 | ALDH1A1 (1.00) | MAPTNPSR1HSD17B10KDM4EPOLB | |
| SCHEMBL15986443 | 0.88 | ALDH1A1 (0.80) | MAPTNPSR1HSD17B10KDM4EPOLB | |
| SCHEMBL16797478 | 0.87 | HSD17B10 (0.79) | MAPTNPSR1HSD17B10KDM4EPOLB | |
| SCHEMBL15983276 | 0.87 | ALDH1A1 (0.79) | MAPTNPSR1HSD17B10KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090226422-A1 | Chemical Inhibitors of Inhibitors of Differentiation | ANGIOGENEX | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090226422-A1 | Chemical Inhibitors of Inhibitors of Differentiation | BRAF, MAPK1, RAF1 | MAPT 2323/4885NPSR1 3006/4885HSD17B10 3456/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.