Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ERN1 | O75460 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | DRD1 | P21728 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30304192 | 1.00 | TDP1 (0.50) | TDP1ERN1ALDH1A1HPGDDRD1 | |
| SCHEMBL613846 | 0.86 | ERN1 (0.47) | TDP1ERN1ALDH1A1HPGDDRD1 | |
| SCHEMBL30480709 | 0.86 | ERN1 (0.47) | TDP1ERN1ALDH1A1HPGDDRD1 | |
| SCHEMBL11260550 | 0.80 | ALDH1A1 (0.50) | ALDH1A1HPGDDRD1MAPTKMT2A | |
| SCHEMBL16793341 | 0.80 | DRD1 (0.42) | ERN1ALDH1A1HPGDDRD1KMT2A | |
| SCHEMBL31662819 | 0.79 | ERN1 (0.43) | ERN1ALDH1A1HPGDDRD1MAPT | |
| SCHEMBL17376694 | 0.79 | ERN1 (0.43) | TDP1ERN1ALDH1A1HPGDDRD1 | |
| SCHEMBL18157268 | 0.79 | SMN1; SMN2 (0.42) | ERN1ALDH1A1DRD1MAPTKMT2A | |
| SCHEMBL21143488 | 0.77 | TDP1 (0.57) | TDP1ERN1ALDH1A1HPGDKMT2A | |
| SCHEMBL29983926 | 0.76 | KDM4E (0.40) | ALDH1A1DRD1L3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116096714-A | Antiviral compounds for the treatment of coronavirus, picornavirus and norovirus infections | 安力高医药股份有限公司 | 2023-05-09 | — | — | CN | disclosed |
| EP-3080114-A1 | FUSED TRICYCLIC IMIDAZOLE DERIVATIVES AS MODULATORS OF TNF ACTIVITY | UCB Biopharma SPRL (BE) | 2016-10-19 | — | — | EP | disclosed |
| WO-2015086527-A1 | FUSED TRICYCLIC IMIDAZOLE DERIVATIVES AS MODULATORS OF TNF ACTIVITY | UCB BIOPHARMA SPRL (BE) | 2015-06-18 | — | — | WO | disclosed |