Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VHL | P40337 | 2/20 | 0.45 |
| ▸ | CCNE1 | P24864 | 6/20 | 0.35 |
| ▸ | CDK2 | P24941 | 6/20 | 0.35 |
| ▸ | GSK3B | P49841 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MLNR | O43193 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1679890 | 0.76 | VHL (0.43) | VHLCCNE1CDK2GSK3BNPC1 | |
| SCHEMBL16748871 | 0.76 | VHL (0.50) | VHLCCNE1CDK2GSK3BNPC1 | |
| SCHEMBL14097635 | 0.75 | VHL (0.55) | VHLCCNE1CDK2GSK3BNPC1 | |
| SCHEMBL1679820 | 0.72 | VHL (0.53) | VHLCCNE1CDK2GSK3BNPC1 | |
| SCHEMBL1136794 | 0.72 | VHL (0.59) | VHLEPHX2P2RX7MEN1KMT2A | |
| SCHEMBL919047 | 0.70 | ABCB1 (0.40) | P2RX7 | |
| SCHEMBL17224786 | 0.70 | THRB (0.33) | — | |
| SCHEMBL17224785 | 0.70 | THRB (0.33) | — | |
| SCHEMBL4093165 | 0.70 | VHL (0.60) | VHLNPC1RAB9AEPHX2P2RX7 | |
| SCHEMBL17224748 | 0.68 | MAPT (0.35) | NPC1RAB9AMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011045271-A1 | HERBICIDALLY ACTIVE, HETEROCYCLYL-SUBSTITUTED PYRIDAZINONES | BAYER CROPSCIENCE AG (DE) | 2011-04-21 | — | — | WO | disclosed |