SCHEMBL16799768

SCHEMBL16799768

c1ccc2c(c1)CCNC2C1NCCc2ccccc21

nearest known ligand 0.70

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PRCP P42785 8/20 0.70
GAA P10253 1/20 0.60
SLC22A1 O15245 1/20 0.55
RECQL P46063 1/20 0.55
TSHR P16473 1/20 0.55
NPSR1 Q6W5P4 1/20 0.55
HTR2C P28335 2/20 0.50
GID4 Q8IVV7 1/20 0.50
HTR2A P28223 1/20 0.50
HTR2B P41595 1/20 0.50
MAPT P10636 1/20 0.46
TAAR1 Q96RJ0 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24017043 1.00 PRCP (0.70) PRCPGAASLC22A1RECQLTSHR
SCHEMBL30368634 1.00 PRCP (0.70) PRCPGAASLC22A1RECQLTSHR
SCHEMBL1738261 0.88 PRCP (0.83) PRCPGAASLC22A1RECQLTSHR
SCHEMBL3865487 0.85 PRCP (0.97) PRCPGAASLC22A1RECQLTSHR
SCHEMBL28083503 0.85 PRCP (0.90) PRCPGAASLC22A1RECQLTSHR
SCHEMBL2793867 0.83 PRCP (1.00) PRCPGAASLC22A1RECQLTSHR
SCHEMBL1011373 0.83 PRCP (1.00) PRCPGAASLC22A1RECQLTSHR
SCHEMBL2795999 0.83 PRCP (1.00) PRCPGAASLC22A1RECQLTSHR
SCHEMBL29768302 0.83 PRCP (1.00) PRCPGAASLC22A1RECQLTSHR
Hydrochloric Acid SCHEMBL2790424 0.82 PRCP (0.97) PRCPGAASLC22A1RECQLTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114306338-B Application of bis-tetrahydroisoquinoline compounds in preparation of medicines for preventing and/or treating coronavirus infection 苏州系统医学研究所 2025-04-25 CN disclosed
EP-4086240-B1 PYRROLIDINONE HERBICIDES FMC CORP (US) 2025-02-05 EP disclosed
US-12077503-B2 Substituted cyclic amides and their use as herbicides FMC CORPORATION (US) 2024-09-03 US disclosed
CN-117777160-A Preparation and application of bi-tetrahydroisoquinoline derivative with cyclic N, O-hemiaminal 南京大学 2024-03-29 CN disclosed
CN-117777160-A Preparation and application of bi-tetrahydroisoquinoline derivative with cyclic N, O-hemiaminal 南京大学 2024-03-29 CN disclosed
CN-117777160-A Preparation and application of bi-tetrahydroisoquinoline derivative with cyclic N, O-hemiaminal 南京大学 2024-03-29 CN disclosed
US-20240025853-A1 SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES FMC CORPORATION 2024-01-25 US disclosed
US-11787765-B2 Substituted cyclic amides and their use as herbicides FMC CORPORATION (US) 2023-10-17 US disclosed
US-20230270111-A1 PYRROLIDINONES HERBICIDES E.I. DU PONT DE NEMOURS AND COMPANY 2023-08-31 US disclosed
US-11634421-B2 Aryl substituted bicyclic compounds as herbicides FMC CORPORATION (US) 2023-04-25 US disclosed
EP-3303321-A1 SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES E. I. du Pont de Nemours and Company (US) 2018-04-11 EP disclosed
EP-3303287-A1 SUBSTITUTED CYCLIC AMIDES AS HERBICIDES E. I. du Pont de Nemours and Company (US) 2018-04-11 EP disclosed
EP-3294743-A1 ARYL SUBSTITUTED BICYCLIC COMPOUNDS AS HERBICIDES E. I. du Pont de Nemours and Company (US) 2018-03-21 EP disclosed
US-20180049437-A1 SUBSTITUTED CYCLIC AMIDES AS HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY 2018-02-22 US disclosed
WO-2016196593-A1 SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES E I DU PONT DE NEMOURS AND COMPANY (US) 2016-12-08 WO disclosed
WO-2016196019-A1 SUBSTITUTED CYCLIC AMIDES AS HERBICIDES E I DU PONT DE NEMOURS AND COMPANY (US) 2016-12-08 WO disclosed
WO-2016182780-A1 ARYL SUBSTITUTED BICYCLIC COMPOUNDS AS HERBICIDES E I DU PONT DE NEMOURS AND COMPANY (US) 2016-11-17 WO disclosed
US-20160297756-A1 PYRROLIDINONES AS HERBICIDES FMC CORPORATION 2016-10-13 US disclosed
EP-3077374-A1 PYRROLIDINONES AS HERBICIDES E. I. du Pont de Nemours and Company (US) 2016-10-12 EP disclosed
WO-2015084796-A1 PYRROLIDINONES AS HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2015-06-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160297756-A1 PYRROLIDINONES AS HERBICIDES DDT, ARG1, PRMT1 PRCP 4056/4885GAA 1776/4885SLC22A1 3233/4885
US-11787765-B2 Substituted cyclic amides and their use as herbicides NIT2, ARG1, CNPY2 PRCP 4828/4885GAA 2449/4885SLC22A1 1519/4885
US-20240025853-A1 SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES NIT2, ARG1, CNPY2 PRCP 4830/4885GAA 2473/4885SLC22A1 1506/4885
US-20230270111-A1 PYRROLIDINONES HERBICIDES DDT, ARG1, CYP1B1 PRCP 4053/4885GAA 1831/4885SLC22A1 3242/4885
US-12077503-B2 Substituted cyclic amides and their use as herbicides NIT2, ARG1, CNPY2 PRCP 4830/4885GAA 2473/4885SLC22A1 1506/4885
US-11634421-B2 Aryl substituted bicyclic compounds as herbicides CYP1B1, CYP1A1, CBR3 PRCP 4645/4885GAA 1102/4885SLC22A1 1854/4885
US-20180049437-A1 SUBSTITUTED CYCLIC AMIDES AS HERBICIDES CYP1A1, CYP1B1, QSOX1 PRCP 4860/4885GAA 2100/4885SLC22A1 1886/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.