Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | ABL1 | P00519 | 2/20 | 0.38 |
| ▸ | IDE | P14735 | 2/20 | 0.38 |
| ▸ | RIN1 | Q13671 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.36 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31707085 | 1.00 | NPSR1 (0.50) | NPSR1TDP1ABL1IDERIN1 | |
| SCHEMBL6554295 | 0.92 | NPSR1 (0.45) | NPSR1TDP1ABL1IDERIN1 | |
| SCHEMBL4403998 | 0.92 | NPSR1 (0.45) | NPSR1TDP1ABL1IDERIN1 | |
| SCHEMBL31181756 | 0.88 | NPSR1 (0.46) | NPSR1TDP1ABL1IDERIN1 | |
| SCHEMBL3051591 | 0.85 | NPSR1 (0.44) | NPSR1TDP1ABL1IDERIN1 | |
| SCHEMBL14141006 | 0.85 | AKR1B1 (0.45) | NPSR1TDP1PPARGMEN1KMT2A | |
| SCHEMBL15298508 | 0.85 | CYP2D6 (0.45) | NPSR1TDP1ABL1IDERIN1 | |
| SCHEMBL29524632 | 0.85 | NPSR1 (0.44) | NPSR1TDP1ABL1IDERIN1 | |
| SCHEMBL23530399 | 0.84 | HDAC3 (0.47) | IDEKEAP1 | |
| SCHEMBL21250151 | 0.84 | HDAC3 (0.47) | IDEKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240115664-A1 | Diketopiperazine Salts for Drug Delivery and Related Methods | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS COLLATERAL AGENT | 2024-04-11 | — | — | US | disclosed |
| US-11872265-B2 | Diketopiperazine salts for drug delivery and related methods | MANNKIND CORPORATION (US) | 2024-01-16 | — | — | US | disclosed |
| US-11872265-B2 | Diketopiperazine salts for drug delivery and related methods | MANNKIND CORPORATION (US) | 2024-01-16 | — | — | US | disclosed |
| US-20210138041-A1 | Diketopiperazine salts for drug delivery and related methods | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS COLLATERAL AGENT | 2021-05-13 | — | — | US | disclosed |
| US-10912821-B2 | Diketopiperazine salts for drug delivery and related methods | MANNKIND CORPORATION (US) | 2021-02-09 | — | — | US | disclosed |
| US-20200164044-A1 | DIKETOPIPERAZINE SALTS FOR DRUG DELIVERY AND RELATED METHODS | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS COLLATERAL AGENT | 2020-05-28 | — | — | US | disclosed |
| US-20190030133-A1 | DIKETOPIPERAZINE SALTS FOR DRUG DELIVERY AND RELATED METHODS | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS COLLATERAL AGENT | 2019-01-31 | — | — | US | disclosed |
| US-20170274050-A1 | Diketopiperazine salts for drug delivery and related methods | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS COLLATERAL AGENT | 2017-09-28 | — | — | US | disclosed |
| US-20170274050-A1 | Diketopiperazine salts for drug delivery and related methods | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS COLLATERAL AGENT | 2017-09-28 | — | — | US | disclosed |
| US-9675674-B2 | Diketopiperazine salts for drug delivery and related methods | MANNKIND CORPORATION (US) | 2017-06-13 | — | — | US | disclosed |
| EP-2314298-A1 | Microparticles comprising diketopiperazine salts, diketomorpholine salts or diketodioxane salts for drug delivery | MannKind Corporation (US) | 2011-04-27 | — | — | EP | disclosed |
| US-20110008448-A1 | Diketopiperazine Salts for Drug Delivery and Related Methods | MANNKIND CORPORATION (US) | 2011-01-13 | — | — | US | disclosed |
| US-20110008448-A1 | Diketopiperazine Salts for Drug Delivery and Related Methods | MANNKIND CORPORATION (US) | 2011-01-13 | — | — | US | disclosed |
| US-7820676-B2 | Diketopiperazine salts for drug delivery and related methods | MANNKIND CORPORATION (US) | 2010-10-26 | — | — | US | disclosed |
| US-7820676-B2 | Diketopiperazine salts for drug delivery and related methods | MANNKIND CORPORATION (US) | 2010-10-26 | — | — | US | disclosed |
| US-7820676-B2 | Diketopiperazine salts for drug delivery and related methods | MANNKIND CORPORATION (US) | 2010-10-26 | — | — | US | disclosed |
| CN-101027057-A | Diketopiperazine, morpholine or dioxane salts for drug delivery | MANNKIND CORP (US) | 2007-08-29 | — | — | CN | disclosed |
| EP-1791542-A1 | DIKETOPIPERAZINE SALTS, DIKETOMORPHOLINE SALTS OR DIKETODIOXANE SALTS FOR DRUG DELIVERY | Mannkind Corporation (US) | 2007-06-06 | — | — | EP | disclosed |
| WO-2006023943-A1 | DIKETOPIPERAZINE SALTS, DIKETOMORPHOLINE SALTS OR DIKETODIOXANE SALTS FOR DRUG DELIVERY | MANNKIND CORPORATION (US) | 2006-03-02 | — | — | WO | disclosed |
| US-20060040953-A1 | Diketopiperazine salts for drug delivery and related methods | MANNKIND CORPORATION (US) | 2006-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110008448-A1 | Diketopiperazine Salts for Drug Delivery and Related Methods | DPP7, DPP4, NPY5R | NPSR1 184/4885TDP1 3492/4885ABL1 2925/4885 |
| US-20170274050-A1 | Diketopiperazine salts for drug delivery and related methods | DPP7, DPP4, NPY5R | NPSR1 184/4885TDP1 3492/4885ABL1 2925/4885 |
| US-20190030133-A1 | DIKETOPIPERAZINE SALTS FOR DRUG DELIVERY AND RELATED METHODS | DPP7, DPP4, NPY5R | NPSR1 184/4885TDP1 3492/4885ABL1 2925/4885 |
| US-20200164044-A1 | DIKETOPIPERAZINE SALTS FOR DRUG DELIVERY AND RELATED METHODS | DPP7, DPP4, NPY5R | NPSR1 184/4885TDP1 3492/4885ABL1 2925/4885 |
| US-20210138041-A1 | Diketopiperazine salts for drug delivery and related methods | DPP7, DPP4, NPY5R | NPSR1 184/4885TDP1 3492/4885ABL1 2925/4885 |
| US-11872265-B2 | Diketopiperazine salts for drug delivery and related methods | DPP7, DPP4, NPY5R | NPSR1 184/4885TDP1 3492/4885ABL1 2925/4885 |
| US-10912821-B2 | Diketopiperazine salts for drug delivery and related methods | DPP7, DPP4, NPY5R | NPSR1 184/4885TDP1 3492/4885ABL1 2925/4885 |
| US-20240115664-A1 | Diketopiperazine Salts for Drug Delivery and Related Methods | DPP7, DPP4, NPY5R | NPSR1 184/4885TDP1 3492/4885ABL1 2925/4885 |
| US-20060040953-A1 | Diketopiperazine salts for drug delivery and related methods | DNPEP, DPP7, NPPA | NPSR1 155/4885TDP1 4363/4885ABL1 4001/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.