Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | IDE | P14735 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.34 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.34 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31707085 | 0.92 | NPSR1 (0.50) | NPSR1TDP1ABL1IDEPPARG | |
| SCHEMBL1679984 | 0.92 | NPSR1 (0.50) | NPSR1TDP1ABL1IDEPPARG | |
| SCHEMBL31408170 | 0.85 | TPSAB1 (0.33) | TPSAB1 | |
| SCHEMBL30300617 | 0.85 | TPSAB1 (0.33) | TPSAB1 | |
| SCHEMBL31181756 | 0.81 | NPSR1 (0.46) | NPSR1TDP1ABL1IDEPPARG | |
| SCHEMBL15298508 | 0.78 | CYP2D6 (0.45) | NPSR1TDP1ABL1IDEPPARG | |
| SCHEMBL29524632 | 0.78 | NPSR1 (0.44) | NPSR1TDP1ABL1IDEPPARG | |
| SCHEMBL6554343 | 0.78 | TSHR (0.40) | TDP1PPARGNR2E3NCOR2TPSAB1 | |
| SCHEMBL3051591 | 0.78 | NPSR1 (0.44) | NPSR1TDP1ABL1IDEPPARG | |
| SCHEMBL14141006 | 0.78 | AKR1B1 (0.45) | NPSR1TDP1PPARGMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389111-A1 | COMPOSITION FOR INHIBITING HIV ACTIVITY EXTRACTED FROM i PAECILOMYCES SP. /i (TOCHU-KASO) J300 | Republic of Korea (KR) | 2004-02-18 | — | — | EP | disclosed |
| WO-2002080921-A1 | COMPOSITION FOR INHIBITING HIV ACTIVITY EXTRACTED FROM PAECILOMYCES SP. (TOCHU-KASO) J300 | REPUBLIC OF KOREA (KR) | 2002-10-17 | — | — | WO | disclosed |