Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MGLL | Q99685 | 1/20 | 0.54 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.50 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.49 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.49 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.49 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.49 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.49 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6052723 | 1.00 | DGKA (0.62) | DGKALMNAKDM4EDUSP3MEN1 | |
| SCHEMBL505106 | 1.00 | DGKA (0.62) | DGKALMNAKDM4EDUSP3MEN1 | |
| SCHEMBL6052685 | 1.00 | DGKA (0.62) | DGKALMNAKDM4EDUSP3MEN1 | |
| SCHEMBL28292733 | 0.98 | DGKA (0.61) | DGKALMNAKDM4EDUSP3MEN1 | |
| SCHEMBL16830136 | 0.97 | DGKA (0.58) | DGKALMNAKDM4EDUSP3MEN1 | |
| SCHEMBL7561059 | 0.94 | DGKA (0.53) | DGKALMNAKDM4EDUSP3MEN1 | |
| SCHEMBL727225 | 0.94 | DGKA (0.53) | DGKALMNAKDM4EDUSP3MEN1 | |
| Propene SCHEMBL11588452 | 0.93 | DGKA (0.54) | DGKALMNAKDM4EDUSP3MEN1 | |
| SCHEMBL3462028 | 0.92 | DGKA (0.61) | DGKALMNAKDM4EDUSP3MEN1 | |
| SCHEMBL750550 | 0.92 | DGKA (0.75) | DGKALMNAKDM4EDUSP3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230201111-A1 | COMPOSITIONS AND METHODS FOR OPHTHALMIC AND/OR OTHER APPLICATIONS | THE JOHNS HOPKINS UNIVERSITY | 2023-06-29 | — | — | US | disclosed |
| US-20170266120-A1 | NANOCRYSTALS, COMPOSITIONS, AND METHODS THAT AID PARTICLE TRANSPORT IN MUCUS | THE JOHNS HOPKINS UNIVERSITY | 2017-09-21 | — | — | US | disclosed |
| US-9737491-B2 | Nanocrystals, compositions, and methods that aid particle transport in mucus | THE JOHNS HOPKINS UNIVERSITY (US) | 2017-08-22 | — | — | US | disclosed |
| US-20170128378-A1 | NANOCRYSTALS, COMPOSITIONS, AND METHODS THAT AID PARTICLE TRANSPORT IN MUCUS | THE JOHNS HOPKINS UNIVERSITY | 2017-05-11 | — | — | US | disclosed |
| US-20160287526-A1 | NANOCRYSTALS, COMPOSITIONS, AND METHODS THAT AID PARTICLE TRANSPORT IN MUCUS | THE JOHNS HOPKINS UNIVERSITY | 2016-10-06 | — | — | US | disclosed |
| US-9393212-B2 | Nanocrystals, compositions, and methods that aid particle transport in mucus | KALA PHARMACEUTICALS, INC. (US) | 2016-07-19 | — | — | US | disclosed |
| US-20150265543-A1 | NANOCRYSTALS, COMPOSITIONS, AND METHODS THAT AID PARTICLE TRANSPORT IN MUCUS | THE JOHNS HOPKINS UNIVERSITY (US) | 2015-09-24 | — | — | US | disclosed |
| US-20150265542-A1 | NANOCRYSTALS, COMPOSITIONS, AND METHODS THAT AID PARTICLE TRANSPORT IN MUCUS | THE JOHNS HOPKINS UNIVERSITY (US) | 2015-09-24 | — | — | US | disclosed |
| US-9056057-B2 | Nanocrystals, compositions, and methods that aid particle transport in mucus | KALA PHARMACEUTICALS, INC. (US) | 2015-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150265543-A1 | NANOCRYSTALS, COMPOSITIONS, AND METHODS THAT AID PARTICLE TRANSPORT IN MUCUS | MUC1, SLC35A1, EPCAM | DGKA 4505/4885LMNA 1966/4885KDM4E 4523/4885 |
| US-20160287526-A1 | NANOCRYSTALS, COMPOSITIONS, AND METHODS THAT AID PARTICLE TRANSPORT IN MUCUS | MUC1, SLC35A1, EPCAM | DGKA 4505/4885LMNA 1966/4885KDM4E 4523/4885 |
| US-20170128378-A1 | NANOCRYSTALS, COMPOSITIONS, AND METHODS THAT AID PARTICLE TRANSPORT IN MUCUS | MUC1, SLC35A1, EPCAM | DGKA 4505/4885LMNA 1966/4885KDM4E 4523/4885 |
| US-20170266120-A1 | NANOCRYSTALS, COMPOSITIONS, AND METHODS THAT AID PARTICLE TRANSPORT IN MUCUS | MUC1, SLC35A1, EPCAM | DGKA 4505/4885LMNA 1966/4885KDM4E 4523/4885 |
| US-20230201111-A1 | COMPOSITIONS AND METHODS FOR OPHTHALMIC AND/OR OTHER APPLICATIONS | MUC1, PDE6C, STRA6 | DGKA 3660/4885LMNA 1275/4885KDM4E 4763/4885 |
| US-20150265542-A1 | NANOCRYSTALS, COMPOSITIONS, AND METHODS THAT AID PARTICLE TRANSPORT IN MUCUS | MUC1, SLC35A1, EPCAM | DGKA 4505/4885LMNA 1966/4885KDM4E 4523/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.