Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | CCR1 | P32246 | 2/20 | 0.46 |
| ▸ | CCR5 | P51681 | 2/20 | 0.46 |
| ▸ | CCR8 | P51685 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | METAP1 | P53582 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.46 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.46 |
| ▸ | HNF4A | P41235 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2734583 | 0.90 | KDM4E (0.56) | TGFBR1LMNAKDM4ECCR1CCR5 | |
| SCHEMBL27992763 | 0.86 | KDM4E (0.52) | TGFBR1LMNAKDM4ECCR1CCR5 | |
| SCHEMBL30525703 | 0.84 | ALDH1A1 (0.50) | TGFBR1LMNAKDM4ECCR1CCR5 | |
| SCHEMBL30336107 | 0.82 | KDM4E (0.52) | TGFBR1LMNAKDM4ECCR1CCR5 | |
| SCHEMBL3364759 | 0.82 | KDM4E (0.56) | TGFBR1LMNAKDM4ECCR1CCR5 | |
| SCHEMBL5463849 | 0.81 | KDM4E (0.50) | LMNAKDM4ECCR1CCR5CCR8 | |
| SCHEMBL31618896 | 0.80 | KDM4E (0.54) | TGFBR1LMNAKDM4ECCR1CCR5 | |
| SCHEMBL29986091 | 0.80 | KDM4E (0.54) | TGFBR1LMNAKDM4ECCR1CCR5 | |
| SCHEMBL30392773 | 0.80 | KDM4E (0.54) | TGFBR1LMNAKDM4ECCR1CCR5 | |
| SCHEMBL27924279 | 0.80 | KDM4E (0.65) | LMNAKDM4ECCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015084021-A1 | NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME | ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) | 2015-06-11 | — | — | WO | disclosed |